Diabetic nephropathy (DN) is associated with an increased morbidity and mortality, resulting
in elevated cost for public health systems. DN is the main cause of chronic kidney disease …

The most problematic issue in clinical nephrology is the relentless and progressive increase
in patients with ESRD (end-stage renal disease) worldwide. The impact of diabetic …

Inflammation is the process by which an organism responds to tissue injury involving both
immune cell recruitment and mediator release. Diverse causes of neuropathic pain are …

Objective Chronic hyperglycemia induces pathogenic changes in the vascular endothelium
and leads to the development of microvascular complications in patients with type 2 …

Background Diabetic nephropathy (DN), the leading cause of end-stage renal disease, is
acknowledged as an independent risk factor for cardiovascular disease, which underlines …

Diabetic kidney disease (DKD) can occur in approximately 30–40% of both type 1 and type
2 diabetic patients. The well-established features of DKD include increased serum glucose …

Diabetes mellitus represents a growing concern, both for public economy and global health.
In fact, it can lead to insidious macrovascular and microvascular complications, impacting …

Diabetes mellitus is one of the metabolic diseases having several complications. Nigella
sativa oil (NSO) might have beneficial effects in the treatment of diabetic complications …

Background: The relationship between diabetic nephropathy, visceral adipose tissue (VAT),
and inflammation has been shown. The neutrophil-to-lymphocyte ratio (NLR) and platelet-to …

Aldose reductase (AR) is an aldo–keto reductase that has been widely investigated as an
enzyme crucially involved in the pathogenesis of chronic complications associated with …