Diabetic vascular diseases: molecular mechanisms and therapeutic strategies
Y Li, Y Liu, S Liu, M Gao, W Wang, K Chen… - Signal transduction and …, 2023 - nature.com
Vascular complications of diabetes pose a severe threat to human health. Prevention and
treatment protocols based on a single vascular complication are no longer suitable for the …
treatment protocols based on a single vascular complication are no longer suitable for the …
Amino acid metabolism in health and disease
ZN Ling, YF Jiang, JN Ru, JH Lu, B Ding… - Signal Transduction and …, 2023 - nature.com
Amino acids are the building blocks of protein synthesis. They are structural elements and
energy sources of cells necessary for normal cell growth, differentiation and function. Amino …
energy sources of cells necessary for normal cell growth, differentiation and function. Amino …
Diet, exercise, and pharmacotherapy for sarcopenia in people with diabetes
Y Hashimoto, F Takahashi, T Okamura, M Hamaguchi… - Metabolism, 2023 - Elsevier
Diabetes prevalence is increasing rapidly in older people, and sarcopenia is prevalent as a
novel complication, particularly in patients with type 2 diabetes mellitus (T2DM). Therefore …
novel complication, particularly in patients with type 2 diabetes mellitus (T2DM). Therefore …
Causal association between obesity, circulating glutamine levels, and depression: a Mendelian randomization study
Context Observational studies indicated obesity and glutamatergic dysfunction as potential
risk factors of depression, and reported disturbance of glutamine metabolism in obese state …
risk factors of depression, and reported disturbance of glutamine metabolism in obese state …
Glutamine and amino acid metabolism as a prognostic signature and therapeutic target in endometrial cancer
L Zhai, X Yang, Y Cheng, J Wang - Cancer Medicine, 2023 - Wiley Online Library
Introduction Endometrial cancer (EC) is the most common female reproductive system
cancer in developed countries with growing incidence and associated mortality, which may …
cancer in developed countries with growing incidence and associated mortality, which may …
Glutamine Ameliorates Liver Steatosis via Regulation of Glycolipid Metabolism and Gut Microbiota in High-Fat Diet-Induced Obese Mice
X Zhou, J Zhang, Y Sun, J Shen, B Sun… - Journal of Agricultural …, 2023 - ACS Publications
Obesity and its associated conditions, such as nonalcoholic fatty liver disease (NAFLD), are
risk factors for health. The aim of this study was to explore the effects of glutamine (Gln) on …
risk factors for health. The aim of this study was to explore the effects of glutamine (Gln) on …
Salbutamol Attenuates Diabetic Skeletal Muscle Atrophy by Reducing Oxidative Stress, Myostatin/GDF-8, and Pro-Inflammatory Cytokines in Rats
Type 2 diabetes is a metabolic disorder that leads to accelerated skeletal muscle atrophy. In
this study, we aimed to evaluate the effect of salbutamol (SLB) on skeletal muscle atrophy in …
this study, we aimed to evaluate the effect of salbutamol (SLB) on skeletal muscle atrophy in …
Selenium polysaccharide form sweet corn cob mediated hypoglycemic effects in vitro and untargeted metabolomics study on type 2 diabetes
J Wang, X Wang, W **u, C Li, S Yu, H Zhu, X Shi… - International Journal of …, 2024 - Elsevier
Type 2 diabetes mellitus (T2D) causes complications due to metabolic disorders besides
increasing blood glucose. Sweet corn cob selenium polysaccharide (SeSCP) is a complex …
increasing blood glucose. Sweet corn cob selenium polysaccharide (SeSCP) is a complex …
13C-Stable isotope resolved metabolomics uncovers dynamic biochemical landscape of gut microbiome-host organ communications in mice
Background Gut microbiome metabolites are important modulators of host health and
disease. However, the overall metabolic potential of the gut microbiome and interactions …
disease. However, the overall metabolic potential of the gut microbiome and interactions …
Butyrate Alleviates High-Fat-Induced Metabolic Disorders Partially through Increasing Systematic Glutamine
Z Fan, S Wang, Y Meng, C Wen, M Xu… - Journal of Agricultural …, 2023 - ACS Publications
Obesity has emerged as a worldwide epidemic. Both butyrate and glutamine counteract
obesity-related metabolic disorders; however, whether and how they synergistically …
obesity-related metabolic disorders; however, whether and how they synergistically …