Global epidemiology of NAFLD-related HCC: trends, predictions, risk factors and prevention

DQ Huang, HB El-Serag, R Loomba - Nature reviews Gastroenterology …, 2021 - nature.com
One quarter of the global population is estimated to have nonalcoholic fatty liver disease
(NAFLD). The incidence of nonalcoholic steatohepatitis (NASH) is projected to increase by …

Non-alcoholic fatty liver disease–a global public health perspective

ZM Younossi - Journal of hepatology, 2019 - Elsevier
As the epidemics of obesity and type 2 diabetes mellitus increase worldwide, the prevalence
of non-alcoholic fatty liver disease (NAFLD) is increasing proportionately. The subtype of …

AASLD practice guidance on prevention, diagnosis, and treatment of hepatocellular carcinoma

AG Singal, JM Llovet, M Yarchoan, N Mehta… - Hepatology, 2023 - journals.lww.com
This guidance document provides an updated approach to the prevention, diagnosis, and
treatment of hepatocellular carcinoma (HCC). The prior American Association for the Study …

The EASL–Lancet Liver Commission: protecting the next generation of Europeans against liver disease complications and premature mortality

TH Karlsen, N Sheron, S Zelber-Sagi, P Carrieri… - The Lancet, 2022 - thelancet.com
Executive summary Liver diseases have become a major health threat across Europe, and
the face of European hepatology is changing due to the cure of viral hepatitis C and the …

Nonalcoholic steatohepatitis: a review

AC Sheka, O Adeyi, J Thompson, B Hameed… - Jama, 2020 - jamanetwork.com
Importance Nonalcoholic steatohepatitis (NASH) is the inflammatory subtype of nonalcoholic
fatty liver disease (NAFLD) and is associated with disease progression, development of …

Epidemiology and surveillance for hepatocellular carcinoma: New trends

AG Singal, P Lampertico, P Nahon - Journal of hepatology, 2020 - Elsevier
The burden of hepatocellular carcinoma (HCC) is highest in East Asia and Africa, although
its incidence and mortality are rapidly rising in the United States and Europe. With the …

Nonalcoholic steatohepatitis-related hepatocellular carcinoma: pathogenesis and treatment

JM Llovet, CE Willoughby, AG Singal… - Nature reviews …, 2023 - nature.com
Nonalcoholic fatty liver disease (NAFLD), including its more severe manifestation,
nonalcoholic steatohepatitis (NASH), has a global prevalence of 20–25% and is a major …

Prevalence, incidence, and outcome of non-alcoholic fatty liver disease in Asia, 1999–2019: a systematic review and meta-analysis

J Li, B Zou, YH Yeo, Y Feng, X **e, DH Lee… - The lancet …, 2019 - thelancet.com
Background Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver
disease worldwide. Asia is a large, heterogeneous area with substantial variation in …

Global trends in hepatocellular carcinoma epidemiology: implications for screening, prevention and therapy

AG Singal, F Kanwal, JM Llovet - Nature reviews Clinical oncology, 2023 - nature.com
Hepatocellular carcinoma (HCC) mortality rates are increasing globally, and particularly in
the Western world. Cirrhosis remains the predominant risk factor for HCC. However …

EASL-EASD-EASO Clinical Practice Guidelines on the management of metabolic dysfunction-associated steatotic liver disease (MASLD)

European Association for the Study of the Liver (EASL)… - Obesity Facts, 2024 - karger.com
Metabolic dysfunction-associated steatotic liver disease (MASLD), previously termed non-
alcoholic fatty liver disease (NAFLD), is defined as steatotic liver disease (SLD) in the …