The chemistry of organic contrast agents in the NIR‐II window

J Mu, M **ao, Y Shi, X Geng, H Li… - Angewandte Chemie …, 2022 - Wiley Online Library
Optical imaging, especially fluorescence and photoacoustic imaging, is a non‐invasive
imaging approach with high spatial and temporal resolution and high sensitivity, compared …

Molecular engineering of NIR‐II fluorophores for improved biomedical detection

Z Lei, F Zhang - Angewandte Chemie International Edition, 2021 - Wiley Online Library
The development of fluorophores for the second near‐infrared window (NIR‐II, 1000–1700
nm) represents an emerging, significant, and vibrant field in analytic chemistry, chemical …

Acceptor engineering for NIR-II dyes with high photochemical and biomedical performance

A Ji, H Lou, C Qu, W Lu, Y Hao, J Li, Y Wu… - nature …, 2022 - nature.com
It is highly important and challenging to develop donor-acceptor-donor structured small-
molecule second near-infrared window (NIR-II) dyes with excellent properties such as water …

NIR-II bioimaging of small organic molecule

Y Su, B Yu, S Wang, H Cong, Y Shen - Biomaterials, 2021 - Elsevier
In recent years, people have been actively exploring new imaging methods with high
biological imaging performance because the clinical image definition and depth in vivo …

Design of NIR-II high performance organic small molecule fluorescent probes and summary of their biomedical applications

X Liu, B Yu, Y Shen, H Cong - Coordination Chemistry Reviews, 2022 - Elsevier
Near-infrared fluorescence imaging has gained a lot of attention in biomedicine by virtue of
its high sensitivity, high specificity, and many other advantages. Moreover, near-infrared II …

Nanocrystals for Deep-Tissue In Vivo Luminescence Imaging in the Near-Infrared Region

Y Yang, Q Jiang, F Zhang - Chemical Reviews, 2023 - ACS Publications
In vivo imaging technologies have emerged as a powerful tool for both fundamental
research and clinical practice. In particular, luminescence imaging in the tissue-transparent …

Small molecular NIR-II fluorophores for cancer phototheranostics

H Dai, Q Shen, J Shao, W Wang, F Gao, X Dong - The Innovation, 2021 - cell.com
Phototheranostics integrates deep-tissue imaging with phototherapy (containing
photothermal therapy and photodynamic therapy), holding great promise in early diagnosis …

The pursuit of polymethine fluorophores with NIR-II emission and high brightness for in vivo applications

X Zhao, F Zhang, Z Lei - Chemical Science, 2022 - pubs.rsc.org
Polymethine cyanine dyes, as the most important class of organic near-infrared-II (NIR-II)
fluorophores, recently received increasing attention due to their high molar extinction …

A Bright, Renal‐Clearable NIR‐II Brush Macromolecular Probe with Long Blood Circulation Time for Kidney Disease Bioimaging

C Yao, Y Chen, M Zhao, S Wang, B Wu… - Angewandte …, 2022 - Wiley Online Library
Early detection of kidney disease is of vital importance due to its current prevalence
worldwide. Fluorescence imaging, especially in the second near‐infrared window (NIR‐II) …

Ultrabright renal-clearable cyanine-protein nanoprobes for high-quality NIR-II angiography and lymphography

J Xu, T Han, Y Wang, F Zhang, M Li, L Bai, X Wang… - Nano Letters, 2022 - ACS Publications
The renal-clearable aspect of imaging agent with minimum toxicity issues and side effects is
essential for clinical translation, yet clinical near-infrared-I/II (NIR-I/II) fluorophores with timely …