Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases

DB Kell - BMC medical genomics, 2009 - Springer
Background The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …

Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's …

DB Kell - Archives of toxicology, 2010 - Springer
Exposure to a variety of toxins and/or infectious agents leads to disease, degeneration and
death, often characterised by circumstances in which cells or tissues do not merely die and …

Serum ferritin is an important inflammatory disease marker, as it is mainly a leakage product from damaged cells

DB Kell, E Pretorius - Metallomics, 2014 - academic.oup.com
Abstract" Serum ferritin" presents a paradox, as the iron storage protein ferritin is not
synthesised in serum yet is to be found there. Serum ferritin is also a well known …

Clinical manifestation and prognostic factor in anti-melanoma differentiation-associated gene 5 antibody-associated interstitial lung disease as a complication of …

T Gono, Y Kawaguchi, T Satoh, M Kuwana… - …, 2010 - academic.oup.com
Objective. The aim of this study is to evaluate the clinical manifestation and prognostic
factors of anti-melanoma differentiation-associated gene 5 (MDA5) antibody-associated …

Effects of daily consumption of honey solution on hematological indices and blood levels of minerals and enzymes in normal individuals

NS Al-Waili - Journal of medicinal food, 2003 - liebertpub.com
Seven men and three women (mean age, 31.2 years; range, 20-45 years) received a strictly
controlled regular diet during a 2-week control period, followed by the regular diet …

Novel biomarkers in autoimmune diseases: prolactin, ferritin, vitamin D, and TPA levels in autoimmune diseases

H Orbach, G Zandman‐Goddard… - Annals of the New …, 2007 - Wiley Online Library
The development of autoimmune diseases may be influenced by hormonal,
immunomodulatory, and metabolic pathways. Prolactin (PRL), ferritin, vitamin D, and the …

Ferritin in autoimmune diseases

G Zandman-Goddard, Y Shoenfeld - Autoimmunity reviews, 2007 - Elsevier
Iron, an essential element for many important cellular functions in all living organisms, can
catalyze the formation of potentially toxic free radicals. Excessive iron is sequestered by …

Association of elevated serum ferritin levels and the risk of gestational diabetes mellitus in pregnant women: The Camden study

X Chen, TO Scholl, TP Stein - Diabetes care, 2006 - Am Diabetes Assoc
OBJECTIVE—We examined the influence of a moderately elevated serum ferritin level at
entry to care on the risk of gestational diabetes mellitus (GDM) and a possible mechanism …

Increased ferritin predicts development and severity of acute interstitial lung disease as a complication of dermatomyositis

T Gono, Y Kawaguchi, M Hara, I Masuda… - …, 2010 - academic.oup.com
Objectives. Acute/subacute interstitial pneumonia (A/SIP) is an intractable and fatal
complication of DM. Since a useful indicator predicting the complication of A/SIP has not …

Heme catabolic pathway in inflammation and immune disorders

B Wu, Y Wu, W Tang - Frontiers in pharmacology, 2019 - frontiersin.org
In recent years, the heme catabolic pathway is considered to play an important regulatory
role in cell protection, apoptosis, inflammation, and other physiological and pathological …