Alternative animal models of aging research

S Holtze, E Gorshkova, S Braude… - Frontiers in Molecular …, 2021 - frontiersin.org
Most research on mechanisms of aging is being conducted in a very limited number of
classical model species, ie, laboratory mouse (Mus musculus), rat (Rattus norvegicus …

[HTML][HTML] The world goes bats: living longer and tolerating viruses

V Gorbunova, A Seluanov, BK Kennedy - Cell Metabolism, 2020 - cell.com
For centuries, people believed that bats possessed sinister powers. Bats are thought to be
ancestral hosts to many deadly viruses affecting humans including Ebola, rabies, and most …

DNA methylation predicts age and provides insight into exceptional longevity of bats

GS Wilkinson, DM Adams, A Haghani, AT Lu… - Nature …, 2021 - nature.com
Exceptionally long-lived species, including many bats, rarely show overt signs of aging,
making it difficult to determine why species differ in lifespan. Here, we use DNA methylation …

Six reference-quality genomes reveal evolution of bat adaptations

D Jebb, Z Huang, M Pippel, GM Hughes… - Nature, 2020 - nature.com
Bats possess extraordinary adaptations, including flight, echolocation, extreme longevity
and unique immunity. High-quality genomes are crucial for understanding the molecular …

[HTML][HTML] Bat pluripotent stem cells reveal unusual entanglement between host and viruses

M Déjosez, A Marin, GM Hughes, AE Morales… - Cell, 2023 - cell.com
Bats are distinctive among mammals due to their ability to fly, use laryngeal echolocation,
and tolerate viruses. However, there are currently no reliable cellular models for studying bat …

Predicting the effects of solar energy development on plants and wildlife in the Desert Southwest, United States

CC Karban, JE Lovich, SM Grodsky… - … and Sustainable Energy …, 2024 - Elsevier
Utility-scale solar energy (USSE) is rapidly expanding and expected to compose the largest
source of renewable-generated electricity in the United States and globally over the coming …

[HTML][HTML] The evolution of aging and lifespan

S Li, JM Vazquez, PH Sudmant - Trends in Genetics, 2023 - cell.com
Aging is a nearly inescapable trait among organisms yet lifespan varies tremendously
across different species and spans several orders of magnitude in vertebrates alone. This …

Aging as a loss of morphostatic information: A developmental bioelectricity perspective

L Pio-Lopez, M Levin - Ageing Research Reviews, 2024 - Elsevier
Maintaining order at the tissue level is crucial throughout the lifespan, as failure can lead to
cancer and an accumulation of molecular and cellular disorders. Perhaps, the most …

[HTML][HTML] The translational potential of studying bat immunity

K Baid, AT Irving, N Jouvenet, A Banerjee - Trends in Immunology, 2024 - cell.com
Molecular studies in bats have led to the discovery of antiviral adaptations that may explain
how some bat species have evolved enhanced immune tolerance towards viruses …

A 50-million-year-old, three-dimensionally preserved bat skull supports an early origin for modern echolocation

SJ Hand, J Maugoust, RMD Beck, MJ Orliac - Current Biology, 2023 - cell.com
Bats are among the most recognizable, numerous, and widespread of all mammals. But
much of their fossil record is missing, and bat origins remain poorly understood, as do the …