Moving beyond regression techniques in cardiovascular risk prediction: applying machine learning to address analytic challenges

BA Goldstein, AM Navar, RE Carter - European heart journal, 2017 - academic.oup.com
Risk prediction plays an important role in clinical cardiology research. Traditionally, most risk
models have been based on regression models. While useful and robust, these statistical …

A systematic review of the applications of artificial intelligence and machine learning in autoimmune diseases

IS Stafford, M Kellermann, E Mossotto, RM Beattie… - NPJ digital …, 2020 - nature.com
Autoimmune diseases are chronic, multifactorial conditions. Through machine learning (ML),
a branch of the wider field of artificial intelligence, it is possible to extract patterns within …

Using recursive feature elimination in random forest to account for correlated variables in high dimensional data

BF Darst, KC Malecki, CD Engelman - BMC genetics, 2018 - Springer
Background Random forest (RF) is a machine-learning method that generally works well
with high-dimensional problems and allows for nonlinear relationships between predictors; …

[책][B] Random forests

R Genuer, JM Poggi, R Genuer, JM Poggi - 2020 - Springer
The general principle of random forests is to aggregate a collection of random decision
trees. The goal is, instead of seeking to optimize a predictor “at once” as for a CART tree, to …

Comparing methods for detecting multilocus adaptation with multivariate genotype–environment associations

BR Forester, JR Lasky, HH Wagner… - Molecular …, 2018 - Wiley Online Library
Identifying adaptive loci can provide insight into the mechanisms underlying local
adaptation. Genotype–environment association (GEA) methods, which identify these loci …

[HTML][HTML] Genome-wide modeling of polygenic risk score in colorectal cancer risk

M Thomas, LC Sakoda, M Hoffmeister… - The American journal of …, 2020 - cell.com
Accurate colorectal cancer (CRC) risk prediction models are critical for identifying
individuals at low and high risk of develo** CRC, as they can then be offered targeted …

How many trees in a random forest?

TM Oshiro, PS Perez, JA Baranauskas - … 2012, Berlin, Germany, July 13-20 …, 2012 - Springer
Random Forest is a computationally efficient technique that can operate quickly over large
datasets. It has been used in many recent research projects and real-world applications in …

Overview of random forest methodology and practical guidance with emphasis on computational biology and bioinformatics

AL Boulesteix, S Janitza, J Kruppa… - … Reviews: Data Mining …, 2012 - Wiley Online Library
The random forest (RF) algorithm by Leo Breiman has become a standard data analysis tool
in bioinformatics. It has shown excellent performance in settings where the number of …

Random forests

A Cutler, DR Cutler, JR Stevens - Ensemble machine learning: Methods …, 2012 - Springer
Random Forests were introduced by Leo Breiman [6] who was inspired by earlier work by
Amit and Geman [2]. Although not obvious from the description in [6], Random Forests are …

Oxidative stress and metabolic perturbations in wooden breast disorder in chickens

B Abasht, MF Mutryn, RD Michalek, WR Lee - PloS one, 2016 - journals.plos.org
This study was conducted to characterize metabolic features of the breast muscle (pectoralis
major) in chickens affected with the Wooden Breast myopathy. Live birds from two purebred …