Long non-coding RNA in the pathogenesis of cancers
Y Chi, D Wang, J Wang, W Yu, J Yang - Cells, 2019 - mdpi.com
The incidence and mortality rate of cancer has been quickly increasing in the past decades.
At present, cancer has become the leading cause of death worldwide. Most of the cancers …
At present, cancer has become the leading cause of death worldwide. Most of the cancers …
LncRNA-mediated regulation of cell signaling in cancer
To date, a large number of long non-coding RNAs (lncRNAs) have been recently discovered
through functional genomics studies. Importantly, lncRNAs have been shown, in many …
through functional genomics studies. Importantly, lncRNAs have been shown, in many …
Integrated genomic characterization of pancreatic ductal adenocarcinoma
We performed integrated genomic, transcriptomic, and proteomic profiling of 150 pancreatic
ductal adenocarcinoma (PDAC) specimens, including samples with characteristic low …
ductal adenocarcinoma (PDAC) specimens, including samples with characteristic low …
Therapeutic targeting of long non-coding RNAs in cancer
Long non-coding RNAs (lncRNAs) represent a significant population of the human
transcriptome. Many lncRNAs exhibit cell-and/or tissue/tumor-specific expression, making …
transcriptome. Many lncRNAs exhibit cell-and/or tissue/tumor-specific expression, making …
Cytoplasmic functions of long noncoding RNAs
Long noncoding RNAs (lncRNAs) are transcripts longer than 200 nucleotides found
throughout the cell that lack protein‐coding function. Their functions are closely linked to …
throughout the cell that lack protein‐coding function. Their functions are closely linked to …
Technological developments in lncRNA biology
S Jathar, V Kumar, J Srivastava, V Tripathi - Long Non Coding RNA …, 2017 - Springer
It is estimated that more than 90% of the mammalian genome is transcribed as non-coding
RNAs. Recent evidences have established that these non-coding transcripts are not junk or …
RNAs. Recent evidences have established that these non-coding transcripts are not junk or …
lncRNAs and microRNAs with a role in cancer development
J Liz, M Esteller - Biochimica et Biophysica Acta (BBA)-Gene Regulatory …, 2016 - Elsevier
Most diseases, including human cancer, are frequently associated with an altered
transcription pattern. The alteration of the transcriptome is not restricted to the production of …
transcription pattern. The alteration of the transcriptome is not restricted to the production of …
LncRNAs in cancer: regulatory and therapeutic implications
A Nandwani, S Rathore, M Datta - Cancer letters, 2021 - Elsevier
Long noncoding RNAs (lncRNAs) comprise a class of RNAs that do not code for proteins but
are critical in regulating diverse cellular processes and maintaining cell function. In doing so …
are critical in regulating diverse cellular processes and maintaining cell function. In doing so …
[HTML][HTML] LncRNA—UCA1 enhances cell proliferation and 5-fluorouracil resistance in colorectal cancer by inhibiting miR-204-5p
Recent preliminary studies reported the in vitro tumor-promoting effects of long non-coding
RNA urothelial carcinoma associated 1 (UCA1) in colorectal cancer (CRC). However, the in …
RNA urothelial carcinoma associated 1 (UCA1) in colorectal cancer (CRC). However, the in …
[HTML][HTML] Long non-coding RNA UICLM promotes colorectal cancer liver metastasis by acting as a ceRNA for microRNA-215 to regulate ZEB2 expression
Long non-coding RNAs (lncRNAs) are involved in the pathology of various tumors, including
colorectal cancer (CRC). However, the role of lncRNA in CRC liver metastasis remains …
colorectal cancer (CRC). However, the role of lncRNA in CRC liver metastasis remains …