Silk‐based materials for biomedical applications

A Leal‐Egaña, T Scheibel - Biotechnology and applied …, 2010 - Wiley Online Library
Since the beginning of civilization, humans have exploited nature as an extraordinary
source of materials for medical applications. Most natural materials comprise biopolymers …

Applications of chondrocyte‐based cartilage engineering: an overview

AR Phull, SH Eo, Q Abbas, M Ahmed… - BioMed research …, 2016 - Wiley Online Library
Chondrocytes are the exclusive cells residing in cartilage and maintain the functionality of
cartilage tissue. Series of biocomponents such as different growth factors, cytokines, and …

High-fidelity tissue engineering of patient-specific auricles for reconstruction of pediatric microtia and other auricular deformities

AJ Reiffel, C Kafka, KA Hernandez, S Popa, JL Perez… - PloS one, 2013 - journals.plos.org
Introduction Autologous techniques for the reconstruction of pediatric microtia often result in
suboptimal aesthetic outcomes and morbidity at the costal cartilage donor site. We therefore …

[HTML][HTML] Injectable disc-derived ECM hydrogel functionalised with chondroitin sulfate for intervertebral disc regeneration

C Borrelli, CT Buckley - Acta Biomaterialia, 2020 - Elsevier
Low back pain resulting from intervertebral disc (IVD) degeneration is a significant
socioeconomic burden. The main effect of the degeneration process involves the alteration …

Cartilage repair: past and future–lessons for regenerative medicine

GJVM Van Osch, M Brittberg, JE Dennis… - Journal of cellular …, 2009 - Wiley Online Library
• Introduction: the impaired repair capacity of cartilage and the beginning of cell therapy‐
Autologous chondrocyte implantation‐Combination products‐Randomized controlled …

Engineered cartilage via self-assembled hMSC sheets with incorporated biodegradable gelatin microspheres releasing transforming growth factor-β1

LD Solorio, EL Vieregge, CD Dhami, PN Dang… - Journal of controlled …, 2012 - Elsevier
Self-assembling cell sheets have shown great potential for use in cartilage tissue
engineering applications, as they provide an advantageous environment for the …

Tissue engineering a model for the human ear: assessment of size, shape, morphology, and gene expression following seeding of different chondrocytes

H Kusuhara, N Isogai, M Enjo, H Otani… - Wound repair and …, 2009 - Wiley Online Library
This study examines the tissue engineering of a human ear model through use of bovine
chondrocytes isolated from four different cartilaginous sites (nasoseptal, articular, costal, and …

Trophic effects of adipose-tissue-derived and bone-marrow-derived mesenchymal stem cells enhance cartilage generation by chondrocytes in co-culture

MM Pleumeekers, L Nimeskern, JLM Koevoet… - PloS one, 2018 - journals.plos.org
Aims Combining mesenchymal stem cells (MSCs) and chondrocytes has great potential for
cell-based cartilage repair. However, there is much debate regarding the mechanisms …

3D printing for tissue engineering in otolaryngology

R Di Gesù, AP Acharya, I Jacobs… - Connective Tissue …, 2020 - Taylor & Francis
Airway and other head and neck disorders affect hundreds of thousands of patients each
year and most require surgical intervention. Among these, congenital deformity that affects …

Introducing a 3-dimensionally printed, tissue-engineered graft for airway reconstruction: a pilot study

TA Goldstein, BD Smith, D Zeltsman… - … –Head and Neck …, 2015 - journals.sagepub.com
Objective: To use 3-dimensional (3D) printing and tissue engineering to create a graft for
laryngotracheal reconstruction (LTR). Study Design: In vitro and in vivo pilot animal study …