The packaging of DNA into chromatin in eukaryotes regulates gene transcription, DNA
replication and DNA repair. ATP-dependent chromatin remodelling enzymes (re) arrange …

Helicases of the superfamily (SF) 1 and 2 are involved in virtually all aspects of RNA and
DNA metabolism. SF1 and SF2 helicases share a catalytic core with high structural …

The evolutionary pressure imposed by phage predation on bacteria and archaea has
resulted in the development of effective anti-phage defence mechanisms, including …

The nucleosome remodelling and histone deacetylase (NuRD; also known as Mi-2) complex
regulates gene expression at the level of chromatin. The NuRD complex has been identified …

RNA helicases are ubiquitous, highly conserved enzymes that participate in nearly all
aspects of RNA metabolism. These proteins bind or remodel RNA or RNA–protein …

Eukaryotic chromatin is kept flexible and dynamic to respond to environmental, metabolic,
and developmental cues through the action of a family of so-called “nucleosome …

Chromatin dynamics play an essential role in regulating the accessibility of genomic DNA for
a variety of nuclear processes, including gene transcription and DNA repair. The …

The ATPase retinoid acid-inducible gene (RIG)-I senses viral RNA in the cytoplasm of
infected cells and subsequently activates cellular antiviral defense mechanisms. RIG-I …

The genus Trichoderma contains fungi with high relevance for humans, with applications in
enzyme production for plant cell wall degradation and use in biocontrol. Here, we provide a …

Nicolaides-Baraitser syndrome (NBS) is characterized by sparse hair, distinctive facial
morphology, distal-limb anomalies and intellectual disability. We sequenced the exomes of …