Molecular imaging is the visualization, characterization, and measurement of biological
processes at the molecular and cellular levels in humans and other living systems …

Copper, an essential micronutrient, controls multiple fundamental processes throughout all
forms of life, such as respiration, cell proliferation and neurotransmitter biosynthesis. High …

The use of radionuclides in medicine is based largely on the discoveries of two critical
concepts, the “tracer principle” and the “magic bullet”. In 1913, George de Hevesy …

Metallic radionuclides possess a variety of half-lives, emission types, energies, and
branching ratios, making it possible to apply them as diagnostic and/or therapeutic agents …

Summation Copper-64 (T1/2= 12.7 hours; β+, 0.653 MeV [17.8%]; β−, 0.579 MeV [38.4%])
has decay characteristics that allow for positron emission tomography (PET) imaging and …

Purpose: The Cancer Imaging Program of the National Cancer Institute convened a
workshop to assess the current status of hypoxia imaging, to assess what is known about the …

Background and Purpose Diacetyl‐bis (4‐methyl‐3‐thiosemicarbazonato) copperII (CuII
(atsm)) ameliorates neurodegeneration and delays disease progression in mouse models of …

The importance of transition metals in biological processes has been well established.
Copper (Cu) is a transition metal that can exist in oxidised and reduced states. This allows it …

Neutral and cationic copper bis (thiosemicarbazone) complexes bearing methyl, phenyl, and
hydrogen, on the diketo-backbone of the ligand have been synthesized. All of them were …

The molecules known as bis (thiosemicarbazones) derived from 1, 2-diones can act as
tetradentate ligands for Cu (II), forming stable, neutral complexes. As a family, these …