One of the hallmark advances in our understanding of metalloprotein function is showcased
in our ability to design new, non-native, catalytically active protein scaffolds. This review …

Construction of discrete, self‐assembled architectures in water has gained significant
interest in recent years as a wide range of applications arises from their defined 3D …

Three-stranded coiled coils are peptide structures constructed from amphipathic heptad
repeats. Here we show that it is possible to form pure heterotrimeric three-stranded coiled …

The design of metallo‐miniproteins advances our understanding of the structural and
functional roles of metals in proteins. We recently designed a metal‐binding WW domain …

New technologies for efficient solar-to-fuel energy conversion will help facilitate a global shift
from dependence on fossil fuels to renewable energy. Nature uses photosynthetic reaction …

LINE-1 (L1) is an autonomous retrotransposon, which acted throughout mammalian
evolution and keeps contributing to human genotypic diversity, genetic disease and cancer …

Herein we report unprecedented location‐dependent, size‐selective binding to designed
lanthanide (Ln3+) sites within miniature protein coiled coil scaffolds. Not only do these …

Metalloproteins are essential to sustain life. Natural evolution optimized them for intricate
structural, regulatory and catalytic functions that cannot be fulfilled by either a protein or a …

The mutual relationship between peptides and metal ions enables metalloproteins to have
crucial roles in biological systems, including structural, sensing, electron transport, and …

The relationship between protein structure and function is one of the greatest puzzles within
biochemistry. De novo metalloprotein design is a way to wipe the board clean and …