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Photoreceptor cells and RPE contribute to the development of diabetic retinopathy
D Tonade, TS Kern - Progress in retinal and eye research, 2021 - Elsevier
Diabetic retinopathy (DR) is a leading cause of blindness. It has long been regarded as
vascular disease, but work in the past years has shown abnormalities also in the neural …
vascular disease, but work in the past years has shown abnormalities also in the neural …
Presence and risk factors for glaucoma in patients with diabetes
Diabetes mellitus represents a growing international public health issue with a near
quadrupling in its worldwide prevalence since 1980. Though it has many known …
quadrupling in its worldwide prevalence since 1980. Though it has many known …
Diabetic retinopathy: from animal models to cellular signaling
PM Pitale, MS Gorbatyuk - International Journal of Molecular Sciences, 2022 - mdpi.com
Diabetic retinopathy (DR) is an ocular complication of diabetes mellitus (DM), a metabolic
disorder characterized by elevation in blood glucose level. The pathogenesis of DR includes …
disorder characterized by elevation in blood glucose level. The pathogenesis of DR includes …
Diabetic retinal neurodegeneration as a form of diabetic retinopathy
D Soni, P Sagar, B Takkar - International Ophthalmology, 2021 - Springer
Purpose To review the evidence supporting diabetic retinal neurodegeneration (DRN) as a
form of diabetic retinopathy. Method Review of literature. Results DRN is recognized to be a …
form of diabetic retinopathy. Method Review of literature. Results DRN is recognized to be a …
Visual dysfunction in diabetes
ED Eggers - Annual review of vision science, 2023 - annualreviews.org
Although diabetic retinopathy (DR) is clinically diagnosed as a vascular disease, many
studies find retinal neuronal and visual dysfunction before the onset of vascular DR. This …
studies find retinal neuronal and visual dysfunction before the onset of vascular DR. This …
The effects of early diabetes on inner retinal neurons
ED Eggers, TA Carreon - Visual neuroscience, 2020 - cambridge.org
Diabetic retinopathy is now well understood as a neurovascular disease. Significant deficits
early in diabetes are found in the inner retina that consists of bipolar cells that receive inputs …
early in diabetes are found in the inner retina that consists of bipolar cells that receive inputs …
Tauroursodeoxycholic acid alleviates endoplasmic reticulum stress-mediated visual deficits in diabetic tie2-TNF transgenic mice via TGR5 signaling
Purpose: This study evaluated if tauroursodeoxycholic acid (TUDCA) alleviates pro-
inflammatory and endoplasmic reticulum (ER) stress-mediated visual deficits in diabetic tie2 …
inflammatory and endoplasmic reticulum (ER) stress-mediated visual deficits in diabetic tie2 …
[HTML][HTML] Dopamine deficiency mediates early rod-driven inner retinal dysfunction in diabetic mice
Purpose: Electroretinograms (ERGs) are abnormal in diabetic retinas before the appearance
of vascular lesions, providing a possible biomarker for diabetic vision loss. Previously, we …
of vascular lesions, providing a possible biomarker for diabetic vision loss. Previously, we …
Long-term functional and structural consequences of primary blast overpressure to the eye
Acoustic blast overpressure (ABO) injury in military personnel and civilians is often
accompanied by delayed visual deficits. However, most animal model studies dealing with …
accompanied by delayed visual deficits. However, most animal model studies dealing with …
ON-type retinal ganglion cells are preferentially affected in STZ-induced diabetic mice
RZ Cui, L Wang, SN Qiao, YC Wang… - … & Visual Science, 2019 - iovs.arvojournals.org
Purpose: We investigate morphologic and physiologic alterations of ganglion cells (GCs) in
a streptozocin (STZ)-induced diabetic mouse model. Methods: Experiments were conducted …
a streptozocin (STZ)-induced diabetic mouse model. Methods: Experiments were conducted …