Neurofilaments (NF) are the most abundant cytoskeletal component of large myelinated
axons from adult central and peripheral nervous system. Here, we provide an overview of …

Microtubule-associated proteins (MAPs) function to regulate the assembly dynamics and
organization of microtubule polymers. Upstream regulation of MAP activities is the major …

Doublecortin (DCX) is required for normal migration of neurons into the cerebral cortex,
since mutations in the human gene cause a disruption of cortical neuronal migration. To …

Nervous system function and plasticity rely on the complex architecture of neuronal networks
elaborated during development, when neurons acquire their specific and complex shape …

Neurons contain abundant subsets of highly stable microtubules that resist depolymerizing
conditions such as exposure to the cold. Stable microtubules are thought to be essential for …

Microtubule-associated proteins (MAPs) are main candidates to stabilize neuronal
microtubules, playing an important role in establishing axon-dendrite polarity. However, how …

Amyotrophic lateral sclerosis is heterogeneous with high variability in the speed of
progression even in cases with a defined genetic cause such as superoxide dismutase 1 …

Mammalian cells cultured in vitro are able to recover from cold stress. However, the
mechanisms activated during cold stress and recovery are still being determined. We here …

Neuronal differentiation and function require extensive stabilization of the microtubule
cytoskeleton. Neurons contain a large proportion of microtubules that resist the cold and …

In the last decades the term Store-operated Ca 2+ entry (SOCE) has been used in the
scientific literature to describe an ubiquitous cellular mechanism that allows recovery of …