[HTML][HTML] Dynamic nuclear polarization for sensitivity enhancement in modern solid-state NMR

ASL Thankamony, JJ Wittmann, M Kaushik… - Progress in nuclear …, 2017 - Elsevier
The field of dynamic nuclear polarization has undergone tremendous developments and
diversification since its inception more than 6 decades ago. In this review we provide an in …

Dynamic nuclear polarization for sensitivity enhancement in biomolecular solid-state NMR

T Biedenbänder, V Aladin, S Saeidpour… - Chemical …, 2022 - ACS Publications
Solid-state NMR with magic-angle spinning (MAS) is an important method in structural
biology. While NMR can provide invaluable information about local geometry on an atomic …

High frequency dynamic nuclear polarization

QZ Ni, E Daviso, TV Can, E Markhasin… - Accounts of chemical …, 2013 - ACS Publications
During the three decades 1980–2010, magic angle spinning (MAS) NMR developed into the
method of choice to examine many chemical, physical, and biological problems. In …

Biomolecular and biological applications of solid-state NMR with dynamic nuclear polarization enhancement

WY Chow, G De Paëpe, S Hediger - Chemical Reviews, 2022 - ACS Publications
Solid-state NMR spectroscopy (ssNMR) with magic-angle spinning (MAS) enables the
investigation of biological systems within their native context, such as lipid membranes, viral …

Direct observation of hierarchical protein dynamics

JR Lewandowski, ME Halse, M Blackledge, L Emsley - Science, 2015 - science.org
One of the fundamental challenges of physical biology is to understand the relationship
between protein dynamics and function. At physiological temperatures, functional motions …

Dynamic nuclear polarization NMR spectroscopy of microcrystalline solids

AJ Rossini, A Zagdoun, F Hegner… - Journal of the …, 2012 - ACS Publications
Dynamic nuclear polarization (DNP) solid-state NMR has been applied to powdered
microcrystalline solids to obtain sensitivity enhancements on the order of 100. Glucose …

Polarizing agents for efficient high field DNP solid-state NMR spectroscopy under magic-angle spinning: from design principles to formulation strategies

G Menzildjian, J Schlagnitweit, G Casano, O Ouari… - Chemical …, 2023 - pubs.rsc.org
Dynamic Nuclear Polarization (DNP) has recently emerged as a cornerstone approach to
enhance the sensitivity of solid-state NMR spectroscopy under Magic Angle Spinning (MAS) …

Integrated high-frequency generator system utilizing the magnetic field of the target application

JR Sirigiri, T Maly - US Patent 8,786,284, 2014 - Google Patents
This invention relates to an integrated high-frequency gen erator system utilizing the
magnetic field of the target appli cation and in one embodiment to Such adapted for use in …

THz dynamic nuclear polarization NMR

EA Nanni, AB Barnes, RG Griffin… - IEEE Transactions on …, 2011 - ieeexplore.ieee.org
Dynamic nuclear polarization (DNP) increases the sensitivity of nuclear magnetic resonance
(NMR) spectroscopy by using high frequency microwaves to transfer the polarization of the …

A high-field cellular DNP-supported solid-state NMR approach to study proteins with sub-cellular specificity

D Beriashvili, R Yao, F D'Amico, M Krafčíková… - Chemical …, 2023 - pubs.rsc.org
Studying the structural aspects of proteins within sub-cellular compartments is of growing
interest. Dynamic nuclear polarization supported solid-state NMR (DNP-ssNMR) is uniquely …