Myofibroblasts are the construction workers of wound healing and repair damaged tissues
by producing and organizing collagen/extracellular matrix (ECM) into scar tissue. Scar tissue …

Hydrogels are highly water-swollen molecular networks that are ideal platforms to create
tissue mimetics owing to their vast and tunable properties. As such, hydrogels are promising …

Introduction Tissues can be soft like brain, bone marrow, and fat, which bear little
mechanical stress, or stiff like muscle, cartilage, and bone, which sustain high levels of …

The nucleus is linked mechanically to the extracellular matrix via multiple polymers that
transmit forces to the nuclear envelope and into the nuclear interior. Here, we review some …

Stem cells mechanosense the stiffness of their microenvironment, which impacts
differentiation. Although tissue hydration anti-correlates with stiffness, extracellular matrix …

The successful transport of drug-and cell-based therapeutics to diseased sites represents a
major barrier in the development of clinical therapies. Targeted delivery can be mediated …

This review describes the role of bone cells and their surrounding matrix in maintaining
bone strength through the process of bone remodeling. Subsequently, this work focusses on …

The intact heart undergoes complex and multiscale remodelling processes in response to
altered mechanical cues. Remodelling of the myocardium is regulated by a combination of …

Osteoarthritis is a degenerative joint disease characterized by pain and disability. It involves
all ages and 70% of people aged> 65 have some degree of osteoarthritis. Natural cartilage …

The Role of Mechanical Loading in Tendon Development, Mainte... : JBJS The Role of
Mechanical Loading in Tendon Development, Maintenance, Injury, and Repair : JBJS JBJS …