Despite having been identified as the organism that causes tuberculosis in 1882,
Mycobacterium tuberculosis has managed to still evade our understanding of the protective …

Despite the advent of new diagnostics, drugs and regimens, tuberculosis (TB) remains a
global public health threat. A significant challenge for TB control efforts has been the …

Antibody features vary with tuberculosis (TB) disease state. Whether clinical variables, such
as age or sex, influence associations between Mycobacterium tuberculosis-specific antibody …

Rapid, accurate, sputum-free tests for tuberculosis (TB) triage and confirmation are urgently
needed to close the widening diagnostic gap. We summarise key technologies and review …

Tuberculosis (TB) is a heterogeneous disease manifesting in a subset of individuals infected
with aerosolized Mycobacterium tuberculosis (Mtb). Unlike human TB, murine infection …

Tuberculosis is an airborne disease caused by Mycobacterium tuberculosis (Mtb) and can
manifest both pulmonary and extrapulmonary disease, including ocular tuberculosis (OTB) …

Blood transcriptomics have revealed major characteristics of the immune response in active
TB, but the signature early after infection is unknown. In a unique clinically and temporally …

Tuberculosis is the leading infectious disease killer globally due to a single pathogen.
Despite wide deployment of standard drug regimens, modern diagnostics and a vaccine …

Tuberculosis (TB) affects around 10 million people worldwide in 2019. Approximately 3.4%
of new TB cases are multidrug-resistant. The gold standard method for detecting …

Tuberculosis (TB) in humans is caused by Mycobacterium tuberculosis (Mtb). It is estimated
that 70 million children (< 15 years) are currently infected with Mtb, with 1.2 million each year …