Lysophosphatidic acid (LPA) is a small ubiquitous lipid found in vertebrate and
nonvertebrate organisms that mediates diverse biological actions and demonstrates …

Oxidative modification of LDL is known to elicit an array of pro-atherogenic responses, but it
is generally underappreciated that oxidized LDL (OxLDL) exists in multiple forms …

Due to the superior photoemission and photostability characteristics, quantum dots (QD) are
novel tools in biological and medical applications. However, the toxicity and mechanism of …

Lysophosphatidic acid (LPA), a water-soluble phospholipid, has gained significant attention
in recent years since the discovery that it acts as a potent signaling molecule with wide …

Lysophosphatidylcholine (LPC) and lysophosphatidic acid (LPA), the most prominent
lysoglycerophospholipids, are emerging as a novel class of inflammatory lipids, joining …

Autotaxin (ATX) is a secreted glycoprotein, widely present in biological fluids including
blood. ATX catalyzes the hydrolysis of lysophosphatidylcholine (LPC) to lysophosphatidic …

Autotaxin (ATX) is a member of the nucleotide pyrophosphatase/phosphodiesterase family
of ectoenzymes that hydrolyzes phosphodiester bonds of various nucleotides. It possesses …

Severe COVID-19 is characterized by acute respiratory distress syndrome (ARDS)-like
hyperinflammation and endothelial dysfunction, that can lead to respiratory and multi organ …

Alternatively activated macrophages express the pattern recognition receptor scavenger
receptor A (SR-A). We demonstrated previously that coculture of macrophages with tumor …

Abstract Sphingosine 1-phosphate (S1P) is a bioactive lipid that can function both
extracellularly and intracellularly to mediate a variety of cellular processes. Using lipid …