Phenotype structuring in collective cell migration: a tutorial of mathematical models and methods

T Lorenzi, KJ Painter, C Villa - arxiv preprint arxiv:2410.13629, 2024 - arxiv.org
Populations are heterogeneous, deviating in numerous ways. Phenotypic diversity refers to
the range of traits or characteristics across a population, where for cells this could be the …

A nonlocal regularization of a generalized Busenberg-Travis cross-diffusion system

A Jüngel, M Vetter, A Zurek - arxiv preprint arxiv:2407.01123, 2024 - arxiv.org
A cross-diffusion system with Lotka-Volterra reaction terms in a bounded domain with no-flux
boundary conditions is analyzed. The system is a nonlocal regularization of a generalized …

Mechanics of finite nonlinear viscoelastic growth for soft biological tissues

N Firouzi, R Garziera, GA Holzapfel, T Rabczuk - Thin-Walled Structures, 2025 - Elsevier
Many soft biological tissues have a kind of rubbery properties and behave viscoelastic. The
main difference between soft biological tissues and rubber-like materials is that they can …

From Finite to Continuous Phenotypes in (Visco-) Elastic Tissue Growth Models

T Dębiec, M Mandal, M Schmidtchen - arxiv preprint arxiv:2409.02904, 2024 - arxiv.org
In this study, we explore a mathematical model for tissue growth focusing on the interplay
between multiple cell subpopulations with distinct phenotypic characteristics. The model …

On the inviscid limit connecting Brinkman's and Darcy's models of tissue growth with nonlinear pressure

C Elbar, J Skrzeczkowski - arxiv preprint arxiv:2306.03752, 2023 - arxiv.org
Several recent papers have addressed modelling of the tissue growth by the multi-phase
models where the velocity is related to the pressure by one of the physical laws (Stoke's …

Nonlocal-to-local convergence of the Cahn-Hilliard equation with degenerate mobility and the Flory-Huggins potential

C Elbar, J Skrzeczkowski - arxiv preprint arxiv:2407.03844, 2024 - arxiv.org
The Cahn-Hilliard equation is a fundamental model for phase separation phenomena. Its
rigorous derivation from the nonlocal aggregation equation, motivated by the desire to link …

Spatial segregation across travelling fronts in individual-based and continuum models for the growth of heterogeneous cell populations

JA Carrillo, T Lorenzi, FR Macfarlane - arxiv preprint arxiv:2412.08535, 2024 - arxiv.org
We consider a partial differential equation model for the growth of heterogeneous cell
populations subdivided into multiple distinct discrete phenotypes. In this model, cells …

Nonlocal approximation of an anisotropic cross-diffusion system

T Dębiec, M Schmidtchen - arxiv preprint arxiv:2412.20188, 2024 - arxiv.org
Localisation limits and nonlocal approximations of degenerate parabolic systems have
experienced a renaissance in recent years. However, only few results cover anisotropic …

Gradient Flow Solutions For Porous Medium Equations with Nonlocal L\'{e} vy-type Pressure

G Foghem, D Padilla-Garza, M Schmidtchen - arxiv preprint arxiv …, 2023 - arxiv.org
We study a porous medium-type equation whose pressure is given by a nonlocal L\'{e} vy
operator associated to a symmetric jump L\'{e} vy kernel. The class of nonlocal operators …

Scaling limits for a population model with growth, division and cross-diffusion

M Doumic-Jauffret, S Hecht, M Hoffmann… - arxiv preprint arxiv …, 2024 - arxiv.org
Originally motivated by the morphogenesis of bacterial microcolonies, the aim of this article
is to explore models through different scales for a spatial population of interacting, growing …