Bond-forming and-breaking reactions at sulfur (IV): sulfoxides, sulfonium salts, sulfur ylides, and sulfinate salts
D Kaiser, I Klose, R Oost, J Neuhaus… - Chemical …, 2019 - ACS Publications
Organosulfur compounds have long played a vital role in organic chemistry and in the
development of novel chemical structures and architectures. Prominent among these …
development of novel chemical structures and architectures. Prominent among these …
Radicals: reactive intermediates with translational potential
This Perspective illustrates the defining characteristics of free radical chemistry, beginning
with its rich and storied history. Studies from our laboratory are discussed along with recent …
with its rich and storied history. Studies from our laboratory are discussed along with recent …
Organic semiconductor photocatalyst can bifunctionalize arenes and heteroarenes
Photoexcited electron-hole pairs on a semiconductor surface can engage in redox reactions
with two different substrates. Similar to conventional electrosynthesis, the primary redox …
with two different substrates. Similar to conventional electrosynthesis, the primary redox …
Green chemistry meets medicinal chemistry: a perspective on modern metal-free late-stage functionalization reactions
The progress of drug discovery and development is paced by milestones reached in organic
synthesis. In the last decade, the advent of late-stage functionalization (LSF) reactions has …
synthesis. In the last decade, the advent of late-stage functionalization (LSF) reactions has …
A cross-dehydrogenative C(sp3)−H heteroarylation via photo-induced catalytic chlorine radical generation
Hydrogen atom abstraction (HAT) from C (sp 3)–H bonds of naturally abundant alkanes for
alkyl radical generation represents a promising yet underexplored strategy in the alkylation …
alkyl radical generation represents a promising yet underexplored strategy in the alkylation …
C–H functionalization of azines
Azines, which are six-membered aromatic compounds containing one or more nitrogen
atoms, serve as ubiquitous structural cores of aromatic species with important applications in …
atoms, serve as ubiquitous structural cores of aromatic species with important applications in …
[HTML][HTML] Perspectives on green synthesis and catalysis
Despite their impressive capacity to access diverse functional groups and to synthesize
structurally complex molecules, the majority of the organic reactions suffers from harsh …
structurally complex molecules, the majority of the organic reactions suffers from harsh …
Direct decarboxylation of trifluoroacetates enabled by iron photocatalysis
S Fernández‐García, VO Chantzakou… - Angewandte Chemie …, 2024 - Wiley Online Library
Trifluoroacetates are the most abundant and accessible sources of trifluoromethyl groups,
which are key components in pharmaceuticals and agrochemicals. The generation of …
which are key components in pharmaceuticals and agrochemicals. The generation of …
Site-selective direct C–H pyridylation of unactivated alkanes by triplet excited anthraquinone
Site-selective C–H functionalization in chemical feedstocks is a challenging and useful
reaction in the broad field of chemical research. Here, we report a modular photochemical …
reaction in the broad field of chemical research. Here, we report a modular photochemical …
Electrophotochemical synthesis facilitated trifluoromethylation of arenes using trifluoroacetic acid
The trifluoromethyl (CF3) group is an essential moiety in medicinal chemistry due to its
unique physicochemical properties. While trifluoroacetic acid (TFA) is an inexpensive and …
unique physicochemical properties. While trifluoroacetic acid (TFA) is an inexpensive and …