This review serves as an introduction to an Immunology Series for the Nephrologist
published in CJASN. It provides a brief overview of the immune system, how it works, and …

Liver allograft rejection remains a significant cause of morbidity and graft failure in liver
transplant recipients. Rejection is caused by the recognition of non-self donor alloantigens …

Over the last 60 years, more than a million patients received hematopoietic cell
transplantation. Having incorporated multiple changes in clinical practices, it remains a …

Tissue-resident memory T cells (TRM) contained at sites of previous infection provide local
protection against reinfection. Whether they form and function in organ transplants where …

Graft-versus-host disease and graft rejection are major complications of allogeneic HLA-
mismatched stem cell transplantation or organ transplantation that are caused by …

Objective: To minimize maintenance immunosuppression in upper-extremity transplantation
to favor the risk-benefit balance of this procedure. Background: Despite favorable outcomes …

Successful engraftment of organ transplants has traditionally relied on preventing the
activation of recipient (host) T cells. Once T-cell activation has occurred, however, stalling …

Investigations over the past two decades are revealing complexities in the regulation of the
innate immune response, and how this response, in turn, controls adaptive immunity …

Acute cellular rejection is common after lung transplantation and is associated with an
increased risk of early chronic rejection. We present combined single-cell RNA and TCR …

Kidney transplantation is considered the favored treatment for patients suffering from end-
stage renal disease, since successful transplantation is associated with longer survival and …