Porphyrins as colorimetric and photometric biosensors in modern bioanalytical systems

K Norvaiša, M Kielmann, MO Senge - ChemBioChem, 2020 - Wiley Online Library
Advances in porphyrin chemistry have provided novel materials and exciting technologies
for bioanalysis such as colorimetric sensor array (CSA), photo‐electrochemical (PEC) …

Understanding the logistics for the distribution of heme in cells

AE Gallio, SSP Fung, A Cammack-Najera, AJ Hudson… - JACS Au, 2021 - ACS Publications
Heme is essential for the survival of virtually all living systems─ from bacteria, fungi, and
yeast, through plants to animals. No eukaryote has been identified that can survive without …

An ingestible bacterial-electronic system to monitor gastrointestinal health

M Mimee, P Nadeau, A Hayward, S Carim, S Flanagan… - Science, 2018 - science.org
Biomolecular monitoring in the gastrointestinal tract could offer rapid, precise disease
detection and management but is impeded by access to the remote and complex …

Engineered probiotics for detection and treatment of inflammatory intestinal diseases

M Barra, T Danino, D Garrido - Frontiers in Bioengineering and …, 2020 - frontiersin.org
Inflammatory intestinal diseases such as Crohn's disease and ulcerative colitis have seen
an increase in their prevalence in develo** countries throughout the current decade …

Recent advances in development of genetically encoded fluorescent sensors

L Sanford, A Palmer - Methods in enzymology, 2017 - Elsevier
Genetically encoded fluorescent sensors are essential tools in modern biological research,
and recent advances in fluorescent proteins (FPs) have expanded the scope of sensor …

A whole-cell bacterial biosensor for blood markers detection in urine

N Barger, I Oren, X Li, M Habib, R Daniel - ACS Synthetic Biology, 2021 - ACS Publications
The early detection of blood in urine (hematuria) can play a crucial role in the treatment of
serious diseases (eg, infections, kidney disease, schistosomiasis, and cancer). Therefore …

Coupling split-lux cassette with a toggle switch in bacteria for ultrasensitive blood markers detection in feces and urine

ZP Zou, Y Yang, J Wang, Y Zhou, BC Ye - Biosensors and Bioelectronics, 2022 - Elsevier
Cell-based biosensors have powerful abilities to sense a variety of signal chemical
molecules. However, compared with commercialized methods, whole-cell biosensors …

Metals enhance the killing of bacteria by bacteriophage in human blood

L Ma, SI Green, BW Trautner, RF Ramig… - Scientific Reports, 2018 - nature.com
Multidrug-resistant bacterial pathogens are a major medical concern. E. coli, particularly the
pathotype extraintestinal pathogenic E. coli (ExPEC), is a leading cause of bloodstream …

[HTML][HTML] Biosensor-based therapy powered by synthetic biology

C Wang, HS Zeng, KX Liu, YN Lin, H Yang… - Smart Materials in …, 2023 - Elsevier
The study of synthetic biology focusing on biosensor systems has resulted from a growing
interest in develo** customized biological devices with desired cellular functions …

A high-throughput method for identifying novel genes that influence metabolic pathways reveals new iron and heme regulation in Pseudomonas aeruginosa

DG Glanville, C Mullineaux-Sanders, CJ Corcoran… - Msystems, 2021 - Am Soc Microbiol
Heme is an essential metabolite for most life on earth. Bacterial pathogens almost
universally require iron to infect a host, often acquiring this nutrient in the form of heme. The …