Immunological shifts during early-stage Parkinson's disease identified with DNA methylation data on longitudinally collected blood samples
Parkinson's disease (PD) is the second most common neurodegenerative disease in the
United States. Decades before motor symptoms manifest, non-motor symptoms such as …
United States. Decades before motor symptoms manifest, non-motor symptoms such as …
Hierarchical deconvolution for extensive cell type resolution in the human brain using DNA methylation
Introduction The human brain comprises heterogeneous cell types whose composition can
be altered with physiological and pathological conditions. New approaches to discern the …
be altered with physiological and pathological conditions. New approaches to discern the …
Deciphering the role of immune cell composition in epigenetic age acceleration: Insights from cell‐type deconvolution applied to human blood epigenetic clocks
Aging is a significant risk factor for various human disorders, and DNA methylation clocks
have emerged as powerful tools for estimating biological age and predicting health‐related …
have emerged as powerful tools for estimating biological age and predicting health‐related …
[HTML][HTML] The Role of Breast Milk Cell-Free DNA in the Regulation of the Neonatal Immune Response
T Rezai, S Fell-Hakai, S Guleria, G Toldi - Nutrients, 2024 - mdpi.com
The neonatal period is a critical phase for the development of the intestinal immune system,
marked by rapid adaptation to the external environment and unique nutritional demands …
marked by rapid adaptation to the external environment and unique nutritional demands …
Matched analysis of detailed peripheral blood and tumor immune microenvironment profiles in bladder cancer
Background: Bladder cancer and therapy responses hinge on immune profiles in the tumor
microenvironment (TME) and blood, yet studies linking tumor-infiltrating immune cells to …
microenvironment (TME) and blood, yet studies linking tumor-infiltrating immune cells to …
DNA Methylation-based Diagnosis and Treatment of Breast Cancer
X Peng, J Zheng, T Liu, Z Zhou, C Song… - Current Cancer Drug …, 2025 - benthamdirect.com
DNA methylation is a key epigenetic modifier involved in tumor formation, invasion, and
metastasis. The development of breast cancer is a complex process, and many studies have …
metastasis. The development of breast cancer is a complex process, and many studies have …
DNA-based cell ty** in menstrual effluent identifies cell type variation by sample collection method: toward noninvasive biomarker development for women's health
Menstrual effluent cell profiles have potential as noninvasive biomarkers of female
reproductive and gynecological health and disease. We used DNA methylation-based cell …
reproductive and gynecological health and disease. We used DNA methylation-based cell …
GENOME-SCALE METHYLATION ANALYSIS IN BLOOD AND TUMOR IDENTIFIES IMMUNE PROFILE, AGE ACCELERATION, AND DNA METHYLATION …
JQ Chen - 2023 - digitalcommons.dartmouth.edu
Bladder cancer patients receive frequent screening due to the high tumor recurrence rate
(more than 60%). Nowadays, the conventional monitoring method relies on cystoscopy …
(more than 60%). Nowadays, the conventional monitoring method relies on cystoscopy …
Glioma immune microenvironment composition calculator (GIMiCC): a method of estimating the proportions of eighteen cell types from DNA methylation microarray …
A scalable platform for cell ty** in the glioma microenvironment can improve tumor
subty** and immune landscape detection as successful immunotherapy strategies …
subty** and immune landscape detection as successful immunotherapy strategies …