MicroRNA signatures in human cancers

GA Calin, CM Croce - Nature reviews cancer, 2006 - nature.com
MicroRNA (miRNA) alterations are involved in the initiation and progression of human
cancer. The causes of the widespread differential expression of miRNA genes in malignant …

Oncomirs—microRNAs with a role in cancer

A Esquela-Kerscher, FJ Slack - Nature reviews cancer, 2006 - nature.com
MicroRNAs (miRNAs) are an abundant class of small non-protein-coding RNAs that function
as negative gene regulators. They regulate diverse biological processes, and bioinformatic …

Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases

X Chen, Y Ba, L Ma, X Cai, Y Yin, K Wang, J Guo… - Cell research, 2008 - nature.com
Dysregulated expression of microRNAs (miRNAs) in various tissues has been associated
with a variety of diseases, including cancers. Here we demonstrate that miRNAs are present …

Genomic and transcriptomic hallmarks of poorly differentiated and anaplastic thyroid cancers

I Landa, T Ibrahimpasic, L Boucai… - The Journal of …, 2016 - Am Soc Clin Investig
BACKGROUND. Poorly differentiated thyroid cancer (PDTC) and anaplastic thyroid cancer
(ATC) are rare and frequently lethal tumors that so far have not been subjected to …

NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses

KD Taganov, MP Boldin, KJ Chang… - Proceedings of the …, 2006 - National Acad Sciences
Activation of mammalian innate and acquired immune responses must be tightly regulated
by elaborate mechanisms to control their onset and termination. MicroRNAs have been …

[HTML][HTML] microRNAs as oncogenes and tumor suppressors

B Zhang, X Pan, GP Cobb, TA Anderson - Developmental biology, 2007 - Elsevier
microRNAs (miRNAs) are a new class of non-protein-coding, endogenous, small RNAs.
They are important regulatory molecules in animals and plants. miRNA regulates gene …

MicroRNAs in body fluids—the mix of hormones and biomarkers

MA Cortez, C Bueso-Ramos, J Ferdin… - Nature reviews Clinical …, 2011 - nature.com
Since the discovery of microRNAs (miRNAs), the study of these small noncoding RNAs has
steadily increased and more than 10,000 papers have already been published. The great …

MicroRNAs in cancer

YS Lee, A Dutta - Annual Review of Pathology: Mechanisms of …, 2009 - annualreviews.org
Within the past few years, studies on microRNA (miRNA) and cancer have burst onto the
scene. Profiling of the miRNome (global miRNA expression levels) has become prevalent …

Molecular genetics and diagnosis of thyroid cancer

YE Nikiforov, MN Nikiforova - Nature Reviews Endocrinology, 2011 - nature.com
Thyroid cancer is a common type of endocrine malignancy, and its incidence has been
steadily increasing in many regions of the world. Initiation and progression of thyroid cancer …

MicroRNA signatures in human ovarian cancer

MV Iorio, R Visone, G Di Leva, V Donati, F Petrocca… - Cancer research, 2007 - AACR
Epithelial ovarian cancer (EOC) is the sixth most common cancer in women worldwide and,
despite advances in detection and therapies, it still represents the most lethal gynecologic …