Intracranial aneurysm subarachnoid hemorrhage (SAH) is a cerebrovascular disorder
associated with high overall mortality. Currently, the underlying mechanisms of pathological …

Abstract Purpose of Review Aneurysmal subarachnoid hemorrhage remains a devastating
disease process despite medical advances made over the past 3 decades. Much of the …

CXC chemokine receptor type 4 (CXCR4) is critical for homeostasis of the adaptive and
innate immune system in some CNS diseases. Bruton's tyrosine kinase (BTK) is an essential …

Ferroptosis is a regulated cell death that characterizes the lethal lipid peroxidation and iron
overload, which may contribute to early brain injury (EBI) pathogenesis after subarachnoid …

Microglia are the brain's resident macrophages that play pivotal roles in immune
surveillance and maintaining homeostasis of the Central Nervous System (CNS). Microglia …

Subarachnoid hemorrhage (SAH) has a high mortality rate and causes long-term disability
in many patients, often associated with cognitive impairment. However, the pathogenesis of …

The notion that the central nervous system is an immunologically immune-exempt organ has
changed over the past two decades, with increasing evidence of strong links and …

Aneurysmal subarachnoid hemorrhage (aSAH) is a devastating disease, which mainly
caused by the rupture of an intracranial aneurysm. Clinical trials have demonstrated that …

Stroke is a sudden and rapidly progressing ischemic or hemorrhagic cerebrovascular
disease. When stroke damages the brain, the immune system becomes hyperactive, leading …

Subarachnoid hemorrhage is a devastating disease with significant mortality and morbidity,
despite advances in treating cerebral aneurysms. There has been recent progress in the …