Antioxidant properties of anthocyanins and their mechanism of action in atherosclerosis

C Garcia, CN Blesso - Free Radical Biology and Medicine, 2021‏ - Elsevier
Atherosclerosis develops due to lipid accumulation in the arterial wall and sclerosis as result
of increased hyperlipidemia, oxidative stress, lipid oxidation, and protein oxidation …

The role of Nrf2 in cardiovascular function and disease

S Satta, AM Mahmoud, FL Wilkinson… - Oxidative medicine …, 2017‏ - Wiley Online Library
Free radicals, reactive oxygen/nitrogen species (ROS/RNS), hydrogen sulphide, and
hydrogen peroxide play an important role in both intracellular and intercellular signaling; …

Molecular biology of atherosclerosis

PN Hopkins - Physiological reviews, 2013‏ - journals.physiology.org
At least 468 individual genes have been manipulated by molecular methods to study their
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …

Heme oxygenase-1, oxidation, inflammation, and atherosclerosis

JA Araujo, M Zhang, F Yin - Frontiers in pharmacology, 2012‏ - frontiersin.org
Atherosclerosis is an inflammatory process of the vascular wall characterized by the
infiltration of lipids and inflammatory cells. Oxidative modifications of infiltrating low-density …

Heme oxygenases in cardiovascular health and disease

A Ayer, A Zarjou, A Agarwal… - Physiological …, 2016‏ - journals.physiology.org
Heme oxygenases are composed of two isozymes, Hmox1 and Hmox2, that catalyze the
degradation of heme to carbon monoxide (CO), ferrous iron, and biliverdin, the latter of …

Generation and biological activities of oxidized phospholipids

VN Bochkov, OV Oskolkova, KG Birukov… - Antioxidants & redox …, 2010‏ - liebertpub.com
Glycerophospholipids represent a common class of lipids critically important for integrity of
cellular membranes. Oxidation of esterified unsaturated fatty acids dramatically changes …

Nrf2 as a potential mediator of cardiovascular risk in metabolic diseases

RM da Costa, D Rodrigues, CA Pereira… - Frontiers in …, 2019‏ - frontiersin.org
Free radicals act as secondary messengers, modulating a number of important biological
processes, including gene expression, ion mobilization in transport systems, protein …

[HTML][HTML] Nrf2 and heme oxygenase-1 involvement in atherosclerosis related oxidative stress

JA Alonso-Piñeiro, A Gonzalez-Rovira… - Antioxidants, 2021‏ - mdpi.com
Atherosclerosis remains the underlying process responsible for cardiovascular diseases
and the high mortality rates associated. This chronic inflammatory disease progresses with …

From metallic cages to transient bioresorbable scaffolds: change in paradigm of coronary revascularization in the upcoming decade?

PW Serruys, HM Garcia-Garcia… - European heart …, 2012‏ - academic.oup.com
Drug-eluting bioresorbable scaffolds (BRSs) may in the near future change drastically the
landscape of percutaneous coronary revascularization. 1 In 1977, when Andreas Gruentzig …

HO-1 overexpression and underexpression: Clinical implications

GS Drummond, J Baum, M Greenberg, D Lewis… - Archives of biochemistry …, 2019‏ - Elsevier
In this review we examine the effects of both over-and under-production of heme oxygenase-
1 (HO-1) and HO activity on a broad spectrum of biological systems and on vascular …