There is increasing interest in develo** a reliable, affordable and accessible disease
biomarker of Parkinson's disease (PD) to facilitate disease modifying PD-trials. Imaging …

The MRI technique diffusion tensor imaging (DTI) is reviewed along with microstructural
changes associated with prodromal A lzheimer's disease (AD) as a potential biomarker for …

We report the first application of a novel diffusion-based MRI method, called diffusional
kurtosis imaging (DKI), to investigate changes in brain tissue microstructure in patients with …

Alzheimer disease (AD) and vascular dementia (VaD) together represent the majority of
dementia cases. Since their neuropsychological profiles often overlap and white matter …

Background: Hippocampal grey matter (GM) atrophy predicts conversion from mild cognitive
impairment (MCI) to Alzheimer's disease (AD). Pilot data suggests that mean diffusivity (MD) …

Previous diffusion tensor imaging (DTI) studies have reported that both mild cognitive
impairment (MCI) and Alzheimer's disease (AD) revealed microstructural changes [fractional …

Background: Early biomarkers of prodromal Alzheimer's disease (AD) are critical both to
initiate interventions and to choose participants for clinical trials. Odor threshold, odor …

The hippocampus is a complex structure located in the mesial temporal lobe that plays a
critical role in cognitive and memory‐related processes. The hippocampal formation consists …

With the prevalence of Alzheimer's disease (AD) predicted to increase substantially over the
coming decades, the development of effective biomarkers for the early detection of the …

Background: Hippocampal atrophy is a characteristic of Alzheimer's disease (AD). However,
alterations in structural connectivity (number of connecting fibers) between the hippocampus …