Acroamine A, a 2-Amino Adenine Alkaloid from the Marine Soft Coral Acrozoanthus australiae and Its Semisynthetic Derivatives That Inhibit cAMP-Dependent Protein …

SPD Senadeera, D Wang, BAP Wilson… - Journal of Natural …, 2024 - ACS Publications
A high throughput screen performed to identify catalytic inhibitors of the oncogenic fusion
form of cAMP-dependent protein kinase A catalytic subunit alpha (J-PKAcα) found an …

Manganaelectro-Catalyzed Cyclization of o-Aminoarylketones with Ammonia: An Approach to 1,2-Dihydroquinazolines

Q Zhong, PL Wang, H Gao, F Liu… - The Journal of Organic …, 2024 - ACS Publications
A manganaelectro-catalyzed cyclization reaction of 2-aminoarylketones with simple alcohols
and ammonia under mild conditions is reported for the first time. The cooperative catalysis …

Sucurchalasins A and B, Sulfur-Containing Heterodimers of a Cytochalasan and a Macrolide from the Endophytic Fungus Aspergillus spelaeus GDGJ-286

JT Zhou, Q Wu, JX Zhao, LL Wu, XH He… - Journal of Natural …, 2024 - ACS Publications
Two sulfur-containing heterodimers of a cytochalasan and a macrolide, sucurchalasins A
and B (1 and 2), and four known cytochalasan monomers (3–6), as well as four known …

Probing the Molecular Mechanisms of Kratom's Antipsychotic Effects through a Multi-modal Computational Approach

S Wimbarti, TE Tallei, BHR Kairupan… - Current …, 2025 - benthamdirect.com
Background Psychosis, marked by detachment from reality, includes symptoms like
hallucinations and delusions. Traditional herbal remedies like kratom are gaining attention …