The impact of disease comorbidities in Alzheimer's disease

JA Santiago, JA Potashkin - Frontiers in aging neuroscience, 2021 - frontiersin.org
A wide range of comorbid diseases is associated with Alzheimer's disease (AD), the most
common neurodegenerative disease worldwide. Evidence from clinical and molecular …

Brain-gut axis dysfunction in the pathogenesis of traumatic brain injury

M Hanscom, DJ Loane… - The Journal of Clinical …, 2021 - Am Soc Clin Investig
Traumatic brain injury (TBI) is a chronic and progressive disease, and management requires
an understanding of both the primary neurological injury and the secondary sequelae that …

A fiber-deprived diet causes cognitive impairment and hippocampal microglia-mediated synaptic loss through the gut microbiota and metabolites

H Shi, X Ge, X Ma, M Zheng, X Cui, W Pan, P Zheng… - Microbiome, 2021 - Springer
Background Cognitive impairment, an increasing mental health issue, is a core feature of the
aging brain and neurodegenerative diseases. Industrialized nations especially, have …

Neuroinflammation represents a common theme amongst genetic and environmental risk factors for Alzheimer and Parkinson diseases

RJ Boyd, D Avramopoulos, LL Jantzie… - Journal of …, 2022 - Springer
Multifactorial diseases are characterized by inter-individual variation in etiology, age of
onset, and penetrance. These diseases tend to be relatively common and arise from the …