The origin and biomedical relevance of cannabigerol
A Jastrząb, I Jarocka-Karpowicz… - International journal of …, 2022 - mdpi.com
The constant search for new pharmacologically active compounds, especially those that do
not exhibit toxic effects, intensifies the interest in plant-based ingredients and their potential …
not exhibit toxic effects, intensifies the interest in plant-based ingredients and their potential …
Cannabis sativa L. as a Natural Drug Meeting the Criteria of a Multitarget Approach to Treatment
A Stasiłowicz, A Tomala, I Podolak… - International journal of …, 2021 - mdpi.com
Cannabis sativa L. turned out to be a valuable source of chemical compounds of various
structures, showing pharmacological activity. The most important groups of compounds …
structures, showing pharmacological activity. The most important groups of compounds …
Phytocannabinoids in the pharmacotherapy of psoriasis
A Wroński, I Jarocka-Karpowicz, A Stasiewicz… - Molecules, 2023 - mdpi.com
Phytocannabinoids are naturally occurring compounds, the main source of which is
Cannabis sativa L. Through direct action or interaction with G protein-coupled receptors …
Cannabis sativa L. Through direct action or interaction with G protein-coupled receptors …
Natural product-based pharmacological studies for neurological disorders
Central nervous system (CNS) disorders and diseases are expected to rise sharply in the
coming years, partly because of the world's aging population. Medicines for the treatment of …
coming years, partly because of the world's aging population. Medicines for the treatment of …
Biosynthesis of phytocannabinoids and structural insights: a review
RK Govindarajan, AK Mishra, KH Cho, KH Kim… - Metabolites, 2023 - mdpi.com
Cannabis belongs to the family Cannabaceae, and phytocannabinoids are produced by the
Cannabis sativa L. plant. A long-standing debate regarding the plant is whether it contains …
Cannabis sativa L. plant. A long-standing debate regarding the plant is whether it contains …
Structural and functional insights into cannabinoid receptors
X Li, L Shen, T Hua, ZJ Liu - Trends in Pharmacological Sciences, 2020 - cell.com
Cannabinoid receptors type 1 (CB1) and 2 (CB2) are widely expressed in the human body,
and are attractive drug targets in the prevention and management of central nervous system …
and are attractive drug targets in the prevention and management of central nervous system …
Antimicrobial and Antiviral (SARS-CoV-2) Potential of Cannabinoids and Cannabis sativa: A Comprehensive Review
Antimicrobial resistance has emerged as a global health crisis and, therefore, new drug
discovery is a paramount need. Cannabis sativa contains hundreds of chemical constituents …
discovery is a paramount need. Cannabis sativa contains hundreds of chemical constituents …
Therapeutic considerations of bioactive compounds in Alzheimer's disease and Parkinson's disease: Dissecting the molecular pathways
BC Phukan, R Roy, I Gahatraj… - Phytotherapy …, 2023 - Wiley Online Library
Leading neurodegenerative diseases Alzheimer's disease (AD) and Parkinson's disease
(PD) are characterized by the impairment of memory and motor functions, respectively …
(PD) are characterized by the impairment of memory and motor functions, respectively …
Attenuation of oxidative stress by cannabinoids and cannabis extracts in differentiated neuronal cells
In this proof-of-concept study, the antioxidant activity of phytocannabinoids, namely
cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC), were investigated using an in vitro …
cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC), were investigated using an in vitro …
The biochemistry of phytocannabinoids and metabolic engineering of their production in heterologous systems
K Blatt-Janmaat, Y Qu - International Journal of Molecular Sciences, 2021 - mdpi.com
The medicinal properties of cannabis and the its legal status in several countries and
jurisdictions has spurred the massive growth of the cannabis economy around the globe …
jurisdictions has spurred the massive growth of the cannabis economy around the globe …