Multiresistant Gram-negative bacteria: the role of high-risk clones in the dissemination of antibiotic resistance

N Woodford, JF Turton… - FEMS microbiology …, 2011 - academic.oup.com
Multilocus sequence ty** reveals that many bacterial species have a clonal structure and
that some clones are widespread. This underlying phylogeny was not revealed by pulsed …

[HTML][HTML] Detection of carbapenemases in Enterobacteriaceae: a challenge for diagnostic microbiological laboratories

J Hrabák, E Chudáčková, CC Papagiannitsis - Clinical Microbiology and …, 2014 - Elsevier
Carbapenemase-producing bacteria have now spread all over the world. Infections caused
by those bacteria are difficult to treat. Therefore, there is an urgent need for accurate and fast …

Multiplex PCR for detection of acquired carbapenemase genes

L Poirel, TR Walsh, V Cuvillier, P Nordmann - Diagnostic microbiology and …, 2011 - Elsevier
A rapid and reliable PCR-based technique was developed for detection of genes encoding
carbapenemases belonging to different classes. Primers were designed to amplify the …

Development of a set of multiplex PCR assays for the detection of genes encoding important β-lactamases in Enterobacteriaceae

C Dallenne, A Da Costa, D Decré… - Journal of …, 2010 - academic.oup.com
Objectives To develop a rapid and reliable tool to detect by multiplex PCR assays the most
frequently widespread β-lactamase genes encoding the OXA-1-like broad-spectrum β …

Global spread of carbapenem-resistant Acinetobacter baumannii

PG Higgins, C Dammhayn, M Hackel… - Journal of Antimicrobial …, 2010 - academic.oup.com
Objectives We have investigated the molecular epidemiology and distribution of
carbapenemase genes in 492 imipenem-non-susceptible Acinetobacter baumannii …

A novel variant, NDM-5, of the New Delhi metallo-β-lactamase in a multidrug-resistant Escherichia coli ST648 isolate recovered from a patient in the United Kingdom

M Hornsey, L Phee, DW Wareham - Antimicrobial agents and …, 2011 - journals.asm.org
ABSTRACT A new variant of the New Delhi metallo-enzyme (NDM) carbapenemase was
identified in a multidrug-resistant Escherichia coli ST648 isolate recovered from the …

Characteristics of extended-spectrum β-lactamase-and carbapenemase-producing Enterobacteriaceae isolates from rivers and lakes in Switzerland

K Zurfluh, H Hächler… - Applied and …, 2013 - journals.asm.org
One of the currently most relevant resistance mechanisms in Enterobacteriaceae is the
production of enzymes that lead to modern expanded-spectrum cephalosporin and even …

Prevalence of VIM- and GIM-producing Acinetobacter baumannii from patients with severe urinary tract infection

SAS Girija, VP Jayaseelan… - Acta microbiologica et …, 2018 - akjournals.com
Carbapenems are administered as the final drug of choice for treating complicated
nosocomial infections caused by multidrug-resistant Acinetobacter baumannii strains. It is …

Molecular mechanisms disrupting porin expression in ertapenem-resistant Klebsiella and Enterobacter spp. clinical isolates from the UK

M Doumith, MJ Ellington, DM Livermore… - Journal of …, 2009 - academic.oup.com
Objectives The aim of this study was to investigate relatedness and molecular mechanism
(s) of ertapenem resistance in clinical isolates of Klebsiella spp.(n= 28) and Enterobacter …

Emergence of colistin resistance in multidrug-resistant Klebsiella pneumoniae and Escherichia coli strains isolated from cancer patients

MM Zafer, HA El-Mahallawy, A Abdulhak… - Annals of clinical …, 2019 - Springer
Background Colistin resistance is mainly driven by alterations in the Gram-negative outer
membrane lipopolysaccharides and is caused, in most cases, by mutations in mgrB gene …