Why are we still a worm world in the 2020s? an overview of risk factors and endemicity for soil-transmitted helminthiasis

AFR Neto, YL Di Christine Oliveira, LM De Oliveira… - Acta parasitologica, 2023 - Springer
Purpose Soil-transmitted helminthiasis (STH) is one of the most common chronic infections
in develo** countries associated with poor socioeconomic and sanitary conditions. The …

Unpacking the Pathogen Box—an open source tool for fighting neglected tropical disease

CGL Veale - ChemMedChem, 2019 - Wiley Online Library
Abstract The Pathogen Box is a 400‐strong collection of drug‐like compounds, selected for
their potential against several of the world's most important neglected tropical diseases …

Prevalence of Intestinal Parasitic Infections and Associated Risk Factors among the First‐Cycle Primary Schoolchildren in Sasiga District, Southwest Ethiopia

B Sitotaw, W Shiferaw - Journal of parasitology research, 2020 - Wiley Online Library
Intestinal parasitic infections (IPIs) have been major public health burdens in low‐income
countries like Ethiopia. Studies in different areas of Ethiopia have shown a high prevalence …

[HTML][HTML] Intestinal parasitic infections: current status and associated risk factors among school aged children in an archetypal African urban slum in Nigeria

VP Gyang, TW Chuang, CW Liao, YL Lee… - Journal of Microbiology …, 2019 - Elsevier
Background/purpose Intestinal parasitic infections (IPIs) among school aged children (SAC)
in Nigeria remains endemic, hence the need for regular surveillance to attract the attention …

Sickness behaviour associated with non-lethal infections in wild primates

RR Ghai, V Fugere, CA Chapman… - … of the Royal …, 2015 - royalsocietypublishing.org
Non-lethal parasite infections are common in wildlife, but there is little information on their
clinical consequences. Here, we pair infection data from a ubiquitous soil-transmitted …

Sirtuin 6 maintains epithelial STAT6 activity to support intestinal tuft cell development and type 2 immunity

X **ong, C Yang, WQ He, J Yu, Y **n, X Zhang… - Nature …, 2022 - nature.com
Dynamic regulation of intestinal epithelial cell (IEC) differentiation is crucial for both
homeostasis and the response to helminth infection. SIRT6 belongs to the NAD+-dependent …

Tumor suppressor p53 regulates intestinal type 2 immunity

CY Chang, J Wang, Y Zhao, J Liu, X Yang… - Nature …, 2021 - nature.com
The role of p53 in tumor suppression has been extensively studied and well-established.
However, the role of p53 in parasitic infections and the intestinal type 2 immunity is unclear …

Ecological risk factors of soil-transmitted helminths infections in Ifedore district, Southwest Nigeria

OE Oyewole, IA Simon-Oke - Bulletin of the National Research Centre, 2022 - Springer
Abstract Background Soil-Transmitted Helminths are a group of parasites that cause
gastrointestinal infections in humans and require the soil to develop into their infective forms …