The chemokines (or chemotactic cytokines) are a large family of small, secreted proteins that
signal through cell surface G protein‐coupled heptahelical chemokine receptors. They are …

Chemokines are chemo tactic cyto kines that control the migratory patterns and positioning
of all immune cells. Although chemokines were initially appreciated as important mediators …

One of the characteristics of the central nervous system is the lack of a classical lymphatic
drainage system. Although it is now accepted that the central nervous system undergoes …

Neuroinflammatory diseases, such as multiple sclerosis, are characterized by invasion of the
brain by autoreactive T cells. The mechanism for how T cells acquire their encephalitogenic …

The metabolic stress occurring in the tumor microenvironment (TME) hampers T cell anti-
tumor immunity by disturbing T cell metabolic and epigenetic programs. Recent studies are …

T cells have crucial roles in protection against infection and cancer. Although the trafficking
of memory T cells around the body is integral to their capacity to provide immune protection …

Tissue-resident memory T cells (TRM cells) provide superior protection against infection in
extralymphoid tissues. Here we found that CD103+ CD8+ TRM cells developed in the skin …

Tissue-resident memory T (Trm) cells constitute a recently identified lymphocyte lineage that
occupies tissues without recirculating. They provide a first response against infections …

The Many Roles of Chemokines and Chemokine Receptors in Inflammation | New England
Journal of Medicine Skip to main content The New England Journal of Medicine homepage …

Resident memory T cells (TRM) form a distinct type of T memory cells that stably resides in
tissues. TRM form an integral part of the immune sensing network and have the ability to …