An overview of the anatomy and biogenesis of salivary glands is important in order to
understand the physiology, functions and disorders associated with saliva. A major disorder …

In biological systems, form and function are inherently correlated. Despite this strong
interdependence, the biological effect of curvature has been largely overlooked or …

Currently, combining biomaterial scaffolds with living stem cells for tissue regeneration is a
main approach for tissue engineering. Mesenchymal stem cells (MSCs) are promising …

Organ-on-a-chip (OOC) systems are engineered nanobiosystems to mimic the
physiochemical environment of a specific organ in the body. Among various components of …

The human salivary gland (SG) has an elegant architecture of epithelial acini, connecting
ductal branching structures, vascular and neuronal networks that together function to …

The mammalian salivary gland develops as a highly branched structure designed to
produce and secrete saliva. This review will focus on research on mouse submandibular …

Salivary gland (SG) dysfunction impairs the life quality of many patients, such as patients
with radiation therapy for head and neck cancer and patients with Sjögren's syndrome …

Radiation therapy for head and neck cancers causes salivary gland dysfunction leading to
permanent xerostomia. Limited progress in the discovery of new therapeutic strategies is …

Dental clinicians have relied for centuries on traditional dental materials (polymers,
ceramics, metals, and composites) to restore oral health and function to patients. Clinical …

There is increasing evidence that surface curvature at a near-cell-scale influences cell
behaviour. Epithelial or endothelial cells lining small acinar or tubular body lumens, as those …