Global burden of hepatitis B virus: current status, missed opportunities and a call for action
Chronic hepatitis B virus (HBV) infection affects about 296 million people worldwide and is
the leading aetiology of cirrhosis and liver cancer globally. Major medical complications also …
the leading aetiology of cirrhosis and liver cancer globally. Major medical complications also …
New approaches to chronic hepatitis B
G Dusheiko, K Agarwal, MK Maini - New England Journal of …, 2023 - Mass Medical Soc
New Approaches to Chronic Hepatitis B | New England Journal of Medicine Skip to main content
The New England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES …
The New England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES …
A liver immune rheostat regulates CD8 T cell immunity in chronic HBV infection
M Bosch, N Kallin, S Donakonda, JD Zhang… - Nature, 2024 - nature.com
Chronic hepatitis B virus (HBV) infection affects 300 million patients worldwide,, in whom
virus-specific CD8 T cells by still ill-defined mechanisms lose their function and cannot …
virus-specific CD8 T cells by still ill-defined mechanisms lose their function and cannot …
CD8 cis-targeted IL-2 drives potent antiviral activity against hepatitis B virus
CD8+ T cells are key antiviral effectors against hepatitis B virus (HBV), yet their number and
function can be compromised in chronic infections. Preclinical HBV models displaying CD8+ …
function can be compromised in chronic infections. Preclinical HBV models displaying CD8+ …
The role of microRNA-185 in the pathogenesis of human diseases: a focus on cancer
MicroRNAs (miRNAs) are a widely-studied class of non-coding RNAs characterized by their
short length (18-25 nucleotides). The precise functions of miRNAs are not well-elucidated; …
short length (18-25 nucleotides). The precise functions of miRNAs are not well-elucidated; …
[HTML][HTML] CXCL13-CXCR5 axis: Regulation in inflammatory diseases and cancer
B Wang, M Wang, D Ao, X Wei - … et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
Chemokine CXC motif ligand 13 (CXCL13), originally identified as a B-cell chemokine, plays
an important role in the immune system. The interaction between CXCL13 and its receptor …
an important role in the immune system. The interaction between CXCL13 and its receptor …
Interferon and interferon-stimulated genes in HBV treatment
Q Li, B Sun, Y Zhuo, Z Jiang, R Li, C Lin, Y **… - Frontiers in …, 2022 - frontiersin.org
Human hepatitis B virus (HBV) is a small enveloped DNA virus with a complex life cycle. It is
the causative agent of acute and chronic hepatitis. HBV can resist immune system …
the causative agent of acute and chronic hepatitis. HBV can resist immune system …
SOTIP is a versatile method for microenvironment modeling with spatial omics data
The rapidly develo** spatial omics generated datasets with diverse scales and modalities.
However, most existing methods focus on modeling dynamics of single cells while ignore …
However, most existing methods focus on modeling dynamics of single cells while ignore …
Endoplasmic reticulum stress-mediated cell death in liver injury
J Zhang, J Guo, N Yang, Y Huang, T Hu, C Rao - Cell death & disease, 2022 - nature.com
The endoplasmic reticulum is an important intracellular organelle that plays an important
role in maintaining cellular homeostasis. Endoplasmic reticulum stress (ERS) and unfolded …
role in maintaining cellular homeostasis. Endoplasmic reticulum stress (ERS) and unfolded …
Priming and Maintenance of Adaptive Immunity in the Liver
The liver's unique characteristics have a profound impact on the priming and maintenance of
adaptive immunity. This review delves into the cellular circuits that regulate adaptive …
adaptive immunity. This review delves into the cellular circuits that regulate adaptive …