Fluorescence-guided surgery is an intraoperative optical imaging method that provides
surgeons with real-time guidance for the delineation of tumours. Currently, in phase 1 and 2 …

Photodynamic therapy is a photochemistry-based approach, approved for the treatment of
several malignant and non-malignant pathologies. It relies on the use of a non-toxic, light …

The presence of lymph node (LN) metastases is an essential prognostic indicator in patients
with head and neck squamous cell carcinoma (HNSCC). This study assessed photoacoustic …

Quantum Dots (QDs) are fluorescent nanoparticles known for their exceptional optical
properties, ie, high fluorescence emission, photostability, narrow emission spectrum, and …

Rationale: Sentinel lymph node biopsy (SLNB) is a well-established minimally invasive
staging procedure that maps the spread of tumour metastases from their primary site to the …

The rate of positive margins in head and neck cancers has remained stagnant over the past
three decades and is consistently associated with poor overall survival. This suggests that …

Frozen section has remained the diagnostic gold standard for intraoperative pathological
evaluation of surgical margins for head and neck specimens. While achieving tumor-free …

In penile squamous cell carcinoma (pSCC), primary surgery aims to obtain oncologically
safe margins while minimizing mutilation. Surgical guidance provided by receptor-specific …

Objectives To determine the utility of 5‐aminolevulinic acid (5‐ALA) fluorescence for
resection of head and neck carcinoma. Methods In this prospective pilot trial, 5‐ALA was …

In patients with head and neck cancer (HNC), surgical removal of cancerous tissue presents
the best overall survival rate. However, failure to obtain negative margins during resection …