Neural stem cells (NSCs) have a unique role in neural regeneration. Cell therapy based on
NSC transplantation is a promising tool for the treatment of nervous system diseases …

The abilities of stem cells to self-renew and form different mature cells expand the
possibilities of applications in cell-based therapies such as tissue recomposition in …

Human pluripotent stem cells (hPSCs) have opened new opportunities for understanding
human development, modelling disease processes and develo** new therapeutics …

Cellular reprogramming using chemically defined conditions, without genetic manipulation,
is a promising approach for generating clinically relevant cell types for regenerative …

Neural stem cell (NSC) transplantation can influence immune responses and suppress
inflammation in the CNS. Metabolites, such as succinate, modulate the phenotype and …

Serotonin neurons located in the raphe nucleus of the hindbrain have crucial roles in
regulating brain functions and have been implicated in various psychiatric disorders. Yet …

Neural stem cells (NSCs) have garnered significant scientific and commercial interest in the
last 15 years. Given their plasticity, defined as the ability to develop into different phenotypes …

It was recently shown that mouse fibroblasts could be reprogrammed into cells of a cardiac
fate by forced expression of multiple transcription factors and microRNAs. For ultimate …

Biophysical cues can improve the direct reprogramming of fibroblasts into neurons that can
be used for therapeutic purposes. However, the effects of a three-dimensional (3D) …

Astrocytes play a critical role in the development and homeostasis of the central nervous
system (CNS). Astrocyte dysfunction results in several neurological and degenerative …