COVID-19: is there evidence for the use of herbal medicines as adjuvant symptomatic therapy?
Background Current recommendations for the self-management of SARS-Cov-2 disease
(COVID-19) include self-isolation, rest, hydration, and the use of NSAID in case of high fever …
(COVID-19) include self-isolation, rest, hydration, and the use of NSAID in case of high fever …
Management of musculoskeletal pain: an update with emphasis on chronic musculoskeletal pain
Musculoskeletal pain is a challenging condition for both patients and physicians. Many
adults have experienced one or more episodes of musculoskeletal pain at some time of their …
adults have experienced one or more episodes of musculoskeletal pain at some time of their …
Paracetamol use during pregnancy—a call for precautionary action
Abstract Paracetamol (N-acetyl-p-aminophenol (APAP), otherwise known as
acetaminophen) is the active ingredient in more than 600 medications used to relieve mild to …
acetaminophen) is the active ingredient in more than 600 medications used to relieve mild to …
Efficacy and safety of paracetamol for spinal pain and osteoarthritis: systematic review and meta-analysis of randomised placebo controlled trials
Objective To investigate the efficacy and safety of paracetamol (acetaminophen) in the
management of spinal pain and osteoarthritis of the hip or knee. Design Systematic review …
management of spinal pain and osteoarthritis of the hip or knee. Design Systematic review …
[BOOK][B] WHO guidelines for the pharmacological and radiotherapeutic management of cancer pain in adults and adolescents
World Health Organization - 2018 - apps.who.int
Cervical cancer is one of the gravest threats to women's lives. It is estimated that over a
million women worldwide currently have cervical cancer. Most of these women have not …
million women worldwide currently have cervical cancer. Most of these women have not …
Essential elements of multimodal analgesia in enhanced recovery after surgery (ERAS) guidelines
A Beverly, AD Kaye, O Ljungqvist… - Anesthesiology …, 2017 - anesthesiology.theclinics.com
Enhanced Recovery After Surgery (ERAS) Society guidelines provide an evidencebased,
multimodal approach to surgical care, to improve outcomes after major operations. The main …
multimodal approach to surgical care, to improve outcomes after major operations. The main …
Long‐term adverse effects of paracetamol–a review
JC McCrae, EE Morrison, IM MacIntyre… - British journal of …, 2018 - Wiley Online Library
Paracetamol (acetaminophen) is the most commonly used drug in the world, with a long
record of use in acute and chronic pain. In recent years, the benefits of paracetamol use in …
record of use in acute and chronic pain. In recent years, the benefits of paracetamol use in …
PharmGKB summary: pathways of acetaminophen metabolism at the therapeutic versus toxic doses
Pharmacokinetics Acetaminophen has a high oral bioavailability (88%); it is well absorbed
and reaches the peak blood concentration within 90min after ingestion [5]. APAP is not …
and reaches the peak blood concentration within 90min after ingestion [5]. APAP is not …
[HTML][HTML] Prolonged sleep deprivation induces a cytokine-storm-like syndrome in mammals
Most animals require sleep, and sleep loss induces serious pathophysiological
consequences, including death. Previous experimental approaches for investigating sleep …
consequences, including death. Previous experimental approaches for investigating sleep …
Analgesic effect of acetaminophen: a review of known and novel mechanisms of action
N Ohashi, T Kohno - Frontiers in Pharmacology, 2020 - frontiersin.org
Acetaminophen is one of the most commonly used analgesic agents for treating acute and
chronic pain. However, its metabolism is complex, and its analgesic mechanisms have not …
chronic pain. However, its metabolism is complex, and its analgesic mechanisms have not …