[HTML][HTML] Influence of the Mediterranean diet on healthy aging

MC Andreo-López, V Contreras-Bolívar… - International Journal of …, 2023‏ - mdpi.com
The life expectancy of the global population has increased. Aging is a natural physiological
process that poses major challenges in an increasingly long-lived and frail population …

Autophagy induction as a therapeutic strategy for neurodegenerative diseases

A Djajadikerta, S Keshri, M Pavel, R Prestil… - Journal of molecular …, 2020‏ - Elsevier
Autophagy is a major, conserved cellular pathway by which cells deliver cytoplasmic
contents to lysosomes for degradation. Genetic studies have revealed extensive links …

[HTML][HTML] Autophagy and apoptosis dysfunction in neurodegenerative disorders

S Ghavami, S Shojaei, B Yeganeh, SR Ande… - Progress in …, 2014‏ - Elsevier
Autophagy and apoptosis are basic physiologic processes contributing to the maintenance
of cellular homeostasis. Autophagy encompasses pathways that target long-lived cytosolic …

[HTML][HTML] Resveratrol: From enhanced biosynthesis and bioavailability to multitargeting chronic diseases

N Pannu, A Bhatnagar - Biomedicine & Pharmacotherapy, 2019‏ - Elsevier
Resveratrol, a phytoalexin with a wide range of pharmacological properties is synthesised
by plants in response to stress, injury, infection or UV radiations. As it is a secondary …

Resveratrol and neuroprotection: impact and its therapeutic potential in Alzheimer's disease

MH Rahman, R Akter, T Bhattacharya… - Frontiers in …, 2020‏ - frontiersin.org
Alzheimer's disease (AD) is a progressive cortex and hippocampal neurodegenerative
disease which ultimately causes cognitively impaired decline in patients. The AD pathogen …

The interaction of polyphenols and the gut microbiota in neurodegenerative diseases

Y Zhang, W Yu, L Zhang, M Wang, W Chang - Nutrients, 2022‏ - mdpi.com
Polyphenols are secondary metabolites of plants and play a potential role in the prevention
and treatment of neurodegenerative diseases (NND) such as Alzheimer's disease (AD) and …

Slowing of neurodegeneration in Parkinson's disease and Huntington's disease: future therapeutic perspectives

AHV Schapira, CW Olanow, JT Greenamyre, E Bezard - The Lancet, 2014‏ - thelancet.com
Several important advances have been made in our understanding of the pathways that
lead to cell dysfunction and death in Parkinson's disease and Huntington's disease. These …

Oxidative and nitrative stress in neurodegeneration

CA Cobb, MP Cole - Neurobiology of disease, 2015‏ - Elsevier
Aerobes require oxygen for metabolism and normal free radical formation. As a result,
maintaining the redox homeostasis is essential for brain cell survival due to their high …

[HTML][HTML] The pharmacology of resveratrol in animals and humans

EJ Park, JM Pezzuto - Biochimica et Biophysica Acta (BBA)-Molecular basis …, 2015‏ - Elsevier
In addition to thousands of research papers related to resveratrol (RSV), approximately 300
review articles have been published. Earlier research tended to focus on pharmacological …

[HTML][HTML] Autophagy as an essential cellular antioxidant pathway in neurodegenerative disease

S Giordano, V Darley-Usmar, J Zhang - Redox biology, 2014‏ - Elsevier
Oxidative stress including DNA damage, increased lipid and protein oxidation, are important
features of aging and neurodegeneration suggesting that endogenous antioxidant protective …