Acute management of traumatic brain injury
Trauma is the leading cause of death in individuals aged 1 to 45 years, with traumatic brain
injury (TBI) responsible for most these deaths; more than 50,000 deaths per year in the …
injury (TBI) responsible for most these deaths; more than 50,000 deaths per year in the …
Potentiating glymphatic drainage minimizes post-traumatic cerebral oedema
Cerebral oedema is associated with morbidity and mortality after traumatic brain injury (TBI).
Noradrenaline levels are increased after TBI,–, and the amplitude of the increase in …
Noradrenaline levels are increased after TBI,–, and the amplitude of the increase in …
Beta-blockers and traumatic brain injury: a systematic review, meta-analysis, and eastern association for the surgery of trauma guideline
Objective: To determine if beta-(β)-blockers improve outcomes after acute traumatic brain
injury (TBI). Background: There have been no new inpatient pharmacologic therapies to …
injury (TBI). Background: There have been no new inpatient pharmacologic therapies to …
Beta‐blocker therapy in severe traumatic brain injury: a prospective randomized controlled trial
Background Observational studies have demonstrated improved outcomes in TBI patients
receiving in‐hospital beta‐blockers. The aim of this study is to conduct a randomized …
receiving in‐hospital beta‐blockers. The aim of this study is to conduct a randomized …
Beta blockers in critically ill patients with traumatic brain injury: results from a multicenter, prospective, observational American Association for the Surgery of Trauma …
BACKGROUND Beta blockers, a class of medications that inhibit endogenous
catecholamines interaction with beta adrenergic receptors, are often administered to …
catecholamines interaction with beta adrenergic receptors, are often administered to …
β-Blockers for traumatic brain injury: a systematic review and meta-analysis
H Ding, L Liao, X Zheng, Q Wang, Z Liu… - Journal of Trauma …, 2021 - journals.lww.com
β-Blockers for traumatic brain injury: A systematic review a... : Journal of Trauma and Acute
Care Surgery β-Blockers for traumatic brain injury: A systematic review and meta-analysis …
Care Surgery β-Blockers for traumatic brain injury: A systematic review and meta-analysis …
Blocking stroke-induced immunodeficiency increases CNS antigen-specific autoreactivity but does not worsen functional outcome after experimental stroke
C Römer, O Engel, K Winek, S Hochmeister… - Journal of …, 2015 - Soc Neuroscience
Stroke-induced immunodepression (SIDS) is an essential cause of poststroke infections.
Pharmacological inhibition of SIDS appears promising in preventing life-threatening …
Pharmacological inhibition of SIDS appears promising in preventing life-threatening …
Traumatic brain injury using mouse models
YP Zhang, J Cai, LBE Shields, N Liu, XM Xu… - Translational stroke …, 2014 - Springer
The use of mouse models in traumatic brain injury (TBI) has several advantages compared
to other animal models including low cost of breeding, easy maintenance, and innovative …
to other animal models including low cost of breeding, easy maintenance, and innovative …
Current clinical trials in traumatic brain injury
Z Ahmed - Brain Sciences, 2022 - mdpi.com
Traumatic brain injury (TBI) is one of the leading causes of morbidity, disability and mortality
across all age groups globally. Currently, only palliative treatments exist, but these are …
across all age groups globally. Currently, only palliative treatments exist, but these are …
Propranolol and mesenchymal stromal cells combine to treat traumatic brain injury
More than 6.5 million patients are burdened by the physical, cognitive, and psychosocial
deficits associated with traumatic brain injury (TBI) in the US Despite extensive efforts to …
deficits associated with traumatic brain injury (TBI) in the US Despite extensive efforts to …