Abstract Carbonic anhydrase (CA, EC 4.2. 1.1) is an enzyme and a very omnipresent zinc
metalloenzyme which catalyzed the reversible hydration and dehydration of carbon dioxide …

The experimental (x-ray, FT-IR NMR and UV-Vis. Spectral data) and theoretical researches
of N-(2-((2-chloro-4, 5-dicyanophenyl) amino) ethyl)-4-methylbenzenesulfonamide molecule …

Sulfonamides are the basic motifs for a whole generation of drugs from a large group of
antibiotics. Currently, research in the field of the new sulfonamide synthesis has received a …

In contemporary medicinal chemistry, employing a singular small molecule to concurrently
multi-target disparate molecular entities is emerging as a potent strategy in the ongoing …

Cancer is a serious threat to human beings and is the second-largest cause of death all over
the globe. Chemotherapy is one of the most common treatments for cancer; however, drug …

In this study, twenty new anthranilic acid hydrazones 6–9 (a–e) were synthesized and their
structures were characterized by Fourier‐transform Infrared (FT‐IR), Nuclear Magnetic …

Innate inflammation beyond a threshold is a significant problem involved in cardiovascular
diseases, cancer, and many other chronic conditions. Cyclooxygenase (COX) enzymes are …

Herein, a series of isoindole‐1, 3‐dione substituted sulfonamide derivatives (3, 4 a–k) were
designed, synthesized, and biologically evaluated, as inhibitors of carbonic anhydrase (CA) …

The surge of scientific interest in the discovery of Nuclear Factor Erythroid 2 (NFE2)-Related
Factor 2 (NRF2)-activating molecules underscores the importance of NRF2 as a therapeutic …

This study reports the synthesis of sulfonamide‐derived Schiff bases as ligands L1 and L2
as well as their transition metal complexes [VO (IV), Fe (II), Co (II), Ni (II), Cu (II), and Zn (II)] …