Chemotaxis enables microorganisms to move according to chemical gradients. Although
this process requires substantial cellular energy, it also affords key physiological benefits …

Salmonella enterica serovar Typhi, the cause of typhoid, is host restricted to humans. S.
Typhi has a monophyletic population structure, indicating that typhoid in humans is a …

Background: The Global Typhoid Genomics Consortium was established to bring together
the typhoid research community to aggregate and analyse Salmonella enterica serovar …

Salmonella enterica serovar Typhimurium is arguably the world's best-understood bacterial
pathogen. However, crucial details about the genetic programs used by the bacterium to …

Bacterial pathogens regulate virulence factor gene expression coordinately in response to
environmental stimuli, including nutrient starvation. The phosphate (Pho) regulon plays a …

Salmonella enterica serovar Typhi (S. Typhi), the aetiologic agent of typhoid fever, is a
human restricted pathogen. The molecular mechanism of Salmonella pathogenicity is …

The knowledge of how organisms fight infections has largely been built upon the ability of
host innate immune molecules to recognize microbial determinants. Although of …

Bacterial chitinases (EC 3.2. 1.14) and chitin-binding proteins (CBPs) play a fundamental
role in the degradation of the ubiquitous biopolymer chitin, and the degradation products …

We propose that microbes that have developed persistent relationships with human hosts
have evolved cross-signalling mechanisms that permit homeostasis that conforms to Nash …

The biogenesis of the Salmonella‐containing vacuole within mammalian cells has been
intensively studied over recent years. However, the ability of Salmonella to sense and adapt …