Evidence for a close bidirectional link between the brain and the gut has led to a paradigm
shift in neurology, especially in the case of Parkinson disease (PD), in which gastrointestinal …

Dementia with Lewy bodies and Parkinson's disease dementia, jointly known as Lewy body
dementia, are common neurodegenerative conditions. Patients with Lewy body dementia …

Depression is one of the most frequent and burdensome non-motor symptoms in
Parkinson's disease (PD), across all stages. Even when its severity is mild, PD depression …

Importance Clinical subty** of Parkinson disease at diagnosis is useful in estimating
disease course and survival. Severity and rate of progression of neuropathologies are …

Advances in medical management of Parkinson's disease (PD) have resulted in living
longer with disability. Although disability worsens over the course of the disease, there are …

RESUMO A doença de Parkinson é a segunda doença neurodegenerativa mais comum,
tendo sido documentado um aumento significativo da sua prevalência nas últimas três …

The use of animals as models of human physiology is, and has been for many years, an
indispensable tool for understanding the mechanisms of human disease. In Parkinson's …

Objective To examine mortality and associated risk factors, including possible effects of mild
cognitive impairment, imaging, and CSF abnormalities, in a community-based population …

Patients with Parkinson's disease present with signs and symptoms of dysregulation of the
peripheral autonomic nervous system that can even precede motor deficits. This …

Parkinson's disease (PD) is a progressive neurodegenerative disorder that primarily affects
elderly people and constitutes a major source of disability worldwide. Notably, the …