Pharmaceutical Particle Engineering via Spray Drying
R Vehring - Pharmaceutical research, 2008 - Springer
This review covers recent developments in the area of particle engineering via spray drying.
The last decade has seen a shift from empirical formulation efforts to an engineering …
The last decade has seen a shift from empirical formulation efforts to an engineering …
Particle engineering for pulmonary drug delivery
AHL Chow, HHY Tong, P Chattopadhyay… - Pharmaceutical …, 2007 - Springer
With the rapidly growing popularity and sophistication of inhalation therapy, there is an
increasing demand for tailor-made inhalable drug particles capable of affording the most …
increasing demand for tailor-made inhalable drug particles capable of affording the most …
Leucine as an excipient in spray dried powder for inhalation
Leucine is a promising excipient with several applications in the development of inhalable
spray-dried powder of high-and low-dose drugs. The addition of leucine has exhibited …
spray-dried powder of high-and low-dose drugs. The addition of leucine has exhibited …
Next generation drying technologies for pharmaceutical applications
RH Walters, B Bhatnagar, S Tchessalov… - Journal of …, 2014 - Elsevier
Drying is a commonly used technique for improving the product stability of biotherapeutics.
Typically, drying is accomplished through freeze-drying, as evidenced by the availability of …
Typically, drying is accomplished through freeze-drying, as evidenced by the availability of …
Mechanistic models facilitate efficient development of leucine containing microparticles for pulmonary drug delivery
AL Feng, MA Boraey, MA Gwin, PR Finlay… - International journal of …, 2011 - Elsevier
Mechanistic models of the spray drying and particle formation processes were used to
conduct a formulation study with minimal use of material and time. A model microparticle …
conduct a formulation study with minimal use of material and time. A model microparticle …
Amino acid-modified spray-dried powders with enhanced aerosolisation properties for pulmonary drug delivery
In this study, the amino acids arginine, aspartic acid, leucine, phenylalanine and threonine
were investigated as 'dispersibility enhancers' in spray-dried powders for inhalation …
were investigated as 'dispersibility enhancers' in spray-dried powders for inhalation …
[KİTAP][B] Thermal analysis of pharmaceuticals
DQM Craig, M Reading - 2006 - taylorfrancis.com
As a result of the Process Analytical Technologies (PAT) initiative launched by the US Food
and Drug Administration (FDA), analytical development is receiving more attention within the …
and Drug Administration (FDA), analytical development is receiving more attention within the …
The influence of formulation components on the aerosolisation properties of spray-dried powders
NR Rabbani, PC Seville - Journal of controlled release, 2005 - Elsevier
Dry powders suitable for inhalation containing β-estradiol, leucine as a dispersibility
enhancer and lactose as a bulking agent were prepared by spray-drying from aqueous …
enhancer and lactose as a bulking agent were prepared by spray-drying from aqueous …
Exploiting gelatin nanocarriers in the pulmonary delivery of methotrexate for lung cancer therapy
Gelatin has many merits that encourage its use in the pulmonary delivery of anticancer
drugs. It is a biodegradable denatured protein which possesses several functional groups …
drugs. It is a biodegradable denatured protein which possesses several functional groups …
Sucrose stearate-based proniosome-derived niosomes for the nebulisable delivery of cromolyn sodium
A Abd-Elbary, HM El-Laithy, MI Tadros - International journal of …, 2008 - Elsevier
A Novel approach was developed for the preparation of controlled release proniosome-
derived niosomes, using sucrose stearates as non-ionic biocompatible surfactants for the …
derived niosomes, using sucrose stearates as non-ionic biocompatible surfactants for the …