Background Chronic and/or extreme stress in early life, often referred to as early adversity,
childhood trauma, or early life stress, has been associated with a wide range of adverse …

Early life adversity (ELA) is a major risk factor for mental illness, but the neurobiological
mechanisms by which ELA increases the risk for future psychopathology are still poorly …

Discovering the processes through which early adverse experiences affect children's
nervous-system development, health, and behavior is critically important for develo** …

Environmental stressors, such as childhood maltreatment, have been recognized to
contribute to the development of depression. Growing evidence suggests that epigenetic …

Background Adverse psychosocial exposures in early life, namely experiences such as child
maltreatment, caregiver stress or depression, and domestic or community violence, have …

Adverse childhood experiences (ACEs) may leave long-lasting neurobiological scars,
increasing the risk of develo** mental disorders in later life. However, no review has …

In the past two decades, much evidence has accumulated unequivocally demonstrating that
child abuse and neglect is associated with a marked increase in risk for major psychiatric …

Childhood trauma confers higher risk of adulthood physical and mental illness; however, the
biological mechanism mediating this association remains largely unknown. Recent research …

Pregnancy is a complex and vulnerable period that presents a number of challenges to
women, including the development of postpartum psychiatric disorders (PPDs). These …

This paper sets out a recent transition in our thinking in relation to psychopathology
associated with personality disorder, in an approach that integrates our thinking about …