Currently, metformin is the first-line medication to treat type 2 diabetes mellitus (T2DM) in
most guidelines and is used daily by> 200 million patients. Surprisingly, the mechanisms …

The role of microbiota in health and diseases is being highlighted by numerous studies
since its discovery. Depending on the localized regions, microbiota can be classified into …

The gut microbiome is associated with diverse diseases,–, but a universal signature of a
healthy or unhealthy microbiome has not been identified, and there is a need to understand …

The levels of the thousands of metabolites in the human plasma metabolome are strongly
influenced by an individual's genetics and the composition of their diet and gut microbiome …

The human body is full of an extensive number of commensal microbes, consisting of
bacteria, viruses, and fungi, collectively termed the human microbiome. The initial …

There is increasing interest in the potential contribution of the gut microbiome to autism
spectrum disorder (ASD). However, previous studies have been underpowered and have …

Objective The microbiome directly affects the balance of pro-inflammatory and anti-
inflammatory responses in the gut. As microbes thrive on dietary substrates, the question …

Diet modulates the gut microbiome, which in turn can impact the immune system. Here, we
determined how two microbiota-targeted dietary interventions, plant-based fiber and …

Variation in the human gut microbiome can reflect host lifestyle and behaviors and influence
disease biomarker levels in the blood. Understanding the relationships between gut …

To study the effect of host genetics on gut microbiome composition, the MiBioGen
consortium curated and analyzed genome-wide genotypes and 16S fecal microbiome data …