Given the extensive and routine use of cardiovascular devices, a major limiting factor to their
success is the thrombotic rate that occurs. This poses direct risk to the patient and requires …

Normal haemostasis is an important physiological mechanism that prevents excessive
bleeding during trauma, whereas the pathological thrombosis especially in diabetics leads …

Platelet adhesion and activation are essential initial processes of arterial and microvascular
hemostasis, where high hydrodynamic forces from the bloodflow impede coagulation. The …

Blood coagulation, which involves a group of complex biochemical reactions, is a crucial
step in hemostasis to stop bleeding at the injury site of a blood vessel. Coagulation …

Diabetes mellitus type 2 (DM2) is a hypercoagulable state with enhanced platelet (PLT)
activation and increased clo ing factor production. Simultaneously, the fibrinolytic cell system …

Platelets upregulate the generation of thrombin and reinforce the fibrin clot which increases
the incidence risk of venous thromboembolism (VTE). However, the role of platelets in the …

In this paper a novel model, based on the smoothed particle hydrodynamics (SPH) method,
is proposed to simulate thrombus formation. This describes the main phases of the …

Aneurysms of saccular shape are usually associated with a slow, almost stagnant blood
flow, as well as a consequent emergence of blood clots. Despite the practical importance …

Thrombosis plays a crucial role in atherosclerosis or in haemostasis when a blood vessel is
injured. This article focuses on using a meshless particle-based Lagrangian numerical …

Thrombosis commonly develops in the left atrial appendage of patients with atrial fibrillation.
The formation of blood clots in atrial appendage is a complex process, which depends on …