Decidualization denotes the transformation of endometrial stromal fibroblasts into
specialized secretory decidual cells that provide a nutritive and immunoprivileged matrix …

Physiological and molecular processes initiated during implantation for pregnancy success
are complex but highly organized. This review primarily highlights adverse ripple effects …

Endometrial disorders represent a major gynaecological burden. Current research models
fail to recapitulate the nature and heterogeneity of these diseases, thereby hampering …

In the healthy endometrium, progesterone and estrogen signaling coordinate in a tightly
regulated, dynamic interplay to drive a normal menstrual cycle and promote an embryo …

Cancer is one of the greatest public health challenges. According to the World Health
Organization (WHO), 9.6 million cancer deaths have been reported in 2018. The most …

The endometrium, which is of crucial importance for reproduction, undergoes dynamic cyclic
tissue remodeling. Knowledge of its molecular and cellular regulation is poor, primarily …

Although the majority of low grade, early stage endometrial cancer patients will have good
survival outcomes with surgery alone, those patients who do recur tend to do poorly. Optimal …

Implantation of the embryo into the uterine endometrium is one of the most finely-regulated
processes that leads to the establishment of a successful pregnancy. A plethora of factors …

The theory of retrograde menstruation as aetiopathogenesis of endometriosis formulated by
John Sampson in 1927 shows clear shortcomings: this does not explain why retrograde …

All mammalian uteri contain glands in the endometrium that develop only or primarily after
birth. Gland development or adenogenesis in the postnatal uterus is intrinsically regulated …