Alcohol consumption by adult women is consistently associated with risk of breast cancer.
Several questions regarding alcohol and breast cancer need to be addressed. Menarche to …

Environmental toxicants can alter epigenetic regulatory features such as DNA methylation
and microRNA expression. As the sensitivity of epigenomic regulatory features may be …

Every year more than 13 million deaths worldwide are due to environmental pollutants, and
approximately 24% of diseases are caused by environmental exposures that might be …

Objective Hypomethylation of LINE-1 elements has emerged as a distinguishing feature in
human cancers. Limited evidence indicates that some LINE-1 elements encode an …

Reduced levels of global DNA methylation are associated with genomic instability and are
independent predictors of cancer risk. Little is known about the environmental determinants …

The impact of cigarette smoking can persist for extended periods following smoking
cessation and may involve epigenetic reprogramming. Changes in DNA methylation …

Alterations in DNA methylation patterns, both at specific loci and overall in the genome, have
been associated with many different health outcomes. In cancer and other diseases, most of …

Dietary and other environmental factors induce epigenetic alterations which may have
important consequences for cancer development. This chapter summarizes current …

Multiple studies have investigated global DNA methylation profiles and gene-specific DNA
methylation in blood-based DNA to develop powerful screening markers for cancer. This …

Lifestyle factors, such as diet, smoking, physical activity, and body weight management, are
known to constitute the majority of cancer causes. Epigenetics has been widely proposed as …