An overview of in silico vaccine design against different pathogens and cancer

K Kardani, A Bolhassani, A Namvar - Expert Review of Vaccines, 2020 - Taylor & Francis
Introduction Due to overcome the hardness of the vaccine design, computational
vaccinology is emerging widely. Prediction of T cell and B cell epitopes, antigen processing …

Design of a multiepitope‐based peptide vaccine against the e protein of human COVID‐19: an immunoinformatics approach

MI Abdelmageed, AH Abdelmoneim… - BioMed research …, 2020 - Wiley Online Library
Background. A new endemic disease has spread across Wuhan City, China, in December
2019. Within few weeks, the World Health Organization (WHO) announced a novel …

A brief review of computer-assisted approaches to rational design of peptide vaccines

A Nandy, SC Basak - International journal of molecular sciences, 2016 - mdpi.com
The growing incidences of new viral diseases and increasingly frequent viral epidemics
have strained therapeutic and preventive measures; the high mutability of viral genes puts …

Immunoinformatics Approach for Epitope‐Based Peptide Vaccine Design and Active Site Prediction against Polyprotein of Emerging Oropouche Virus

UK Adhikari, M Tayebi… - Journal of immunology …, 2018 - Wiley Online Library
Oropouche virus (OROV) is an emerging pathogen which causes Oropouche fever and
meningitis in humans. Several outbreaks of OROV in South America, especially in Brazil …

Design of an epitope-based peptide vaccine against spike protein of human coronavirus: an in silico approach

AR Oany, AA Emran, TP Jyoti - Drug design, development and …, 2014 - Taylor & Francis
Human coronavirus (HCoV), a member of Coronaviridae family, is the causative agent of
upper respiratory tract infections and “atypical pneumonia”. Despite severe epidemic …

Conserved B and T cell epitopes prediction of ebola virus glycoprotein for vaccine development: an immuno-informatics approach

B Ahmad, UA Ashfaq, M Rahman, MS Masoud… - Microbial …, 2019 - Elsevier
Ebola virus (EBOV), a non-segmented single-stranded RNA virus, is often-most transmitted
through body fluids like sweat, tears, saliva, and nasal secretions. Till date, there is no …

Epitope-based immunoinformatics approach on nucleocapsid protein of severe acute respiratory syndrome-coronavirus-2

A Rakib, SA Sami, MA Islam, S Ahmed, FB Faiz… - Molecules, 2020 - mdpi.com
With an increasing fatality rate, severe acute respiratory syndrome-coronavirus-2 (SARS-
CoV-2) has emerged as a promising threat to human health worldwide. Recently, the World …

In silico formulation of a next-generation multiepitope vaccine for use as a prophylactic candidate against Crimean-Congo hemorrhagic fever

R Alam, A Samad, F Ahammad, SM Nur, AA Alsaiari… - BMC medicine, 2023 - Springer
Abstract Background Crimean-Congo hemorrhagic fever (CCHF) is a widespread disease
transmitted to humans and livestock animals through the bite of infected ticks or close …

Immunoinformatics prediction of overlap** CD8+ T-cell, IFN-γ and IL-4 inducer CD4+ T-cell and linear B-cell epitopes based vaccines against COVID-19 (SARS …

AJ Fatoba, L Maharaj, VT Adeleke, M Okpeku… - Vaccine, 2021 - Elsevier
At the beginning of the year 2020, the world was struck with a global pandemic virus referred
to as SARS-CoV-2 (COVID-19) which has left hundreds of thousands of people dead. To …

Development of HPV16,18,31,45 E5 and E7 peptides-based vaccines predicted by immunoinformatics tools

A Namvar, HA Panahi, E Agi, A Bolhassani - Biotechnology Letters, 2020 - Springer
Objectives Viral oncoproteins are ideal targets in therapeutic vaccines for functional
inhibition of human papillomaviruses (HPVs). Herein, we designed the peptide constructs …